|
Gastroenterology / Review
Mesenchymal stem cell therapy for liver fibrosis
Young Woo Eom, Kwang Yong Shim, Soon Koo Baik
Korean J Intern Med. 2015;30(5):580-589. Published online August 27, 2015
Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation; however, transplantation is limited by a shortage of donor organs, surgical complications, immunological rejection, and high medical costs. Recently, mesenchymal stem cell (MSC) therapy has been suggested ..
|
|
|
Gastroenterology / Review
A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers
Chen-Shuan Chung, Tsung-Hsien Chiang, Yi-Chia Lee
Korean J Intern Med. 2015;30(5):559-570. Published online August 27, 2015
An idiopathic peptic ulcer is defined as an ulcer with unknown cause or an ulcer that appears to arise spontaneously. The first step in treatment is to exclude common possible causes, including Helicobacter pylori infection, infection with other pathogens, ulcerogenic drugs, and uncommon dise..
|
|
|
Infectious diseases / Original Article
Drug utilization review of mupirocin ointment in a Korean university-affiliated hospital
Sung Hee Youn, Seung Soon Lee, Sukyeon Kim, Jeong-a Lee, Bum Joon Kim, Jounghee Kim, Hye-kyung Han, Jae-Seok Kim
Korean J Intern Med. 2015;30(4):515-520. Published online June 29, 2015
Background/Aims: Intranasa l mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an over-the-counter drug..
|
|
|
Infectious diseases / Original Article
Infections after lung transplantation: time of occurrence, sites, and microbiologic etiologies
Ji Hyun Yun, Sang-Oh Lee, Kyung-Wook Jo, Se Hoon Choi, Jina Lee, Eun Jin Chae, Kyung-Hyun Do, Dae-Kee Choi, In-Cheol Choi, Sang-Bum Hong, Tae Sun Shim, Hyeong Ryul Kim, Dong Kwan Kim, Seung-Il Park
Korean J Intern Med. 2015;30(4):506-514. Published online June 29, 2015
Background/Aims: Infections are major causes of both early and late death after lung transplantation (LT). The development of prophylaxis strategies has altered the epidemiology of post-LT infections; however, recent epidemiological data are limited. We evaluated infections after LT at our instituti..
|
|
|
Pulmonology / Original Article
A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock
Jung-Wan Yoo, Ju Ry Lee, Youn Kyung Jung, Sun Hui Choi, Jeong Suk Son, Byung Ju Kang, Tai Sun Park, Jin-Won Huh, Chae-Man Lim, Younsuck Koh, Sang Bum Hong
Korean J Intern Med. 2015;30(4):471-477. Published online June 29, 2015
Background/Aims: The modified early warning score (MEWS) is used to predict patient intensive care unit (ICU) admission and mortality. Lactate (LA) in the blood lactate (BLA) is measured to evaluate disease severity and treatment efficacy in patients with severe sepsis/septic shock. The usefulness o..
|
|
|
Cardiology / Original Article
Prognostic value of hyponatremia in heart failure patients: an analysis of the Clinical Characteristics and Outcomes in the Relation with Serum Sodium Level in Asian Patients Hospitalized for Heart Failure (COAST) study
[editorial]
Byung-Su Yoo, Jin Joo Park, Dong-Ju Choi, Seok-Min Kang, Juey-Jen Hwang, Shing-Jong Lin, Ming-Shien Wen, Jian Zhang, Junbo Ge, on behalf of the COAST investigators
Korean J Intern Med. 2015;30(4):460-470. Published online June 29, 2015
Background/Aims: Hyponatremia is a well-known risk factor for poor outcomes in Western studies of heart failure (HF) patients. We evaluated the predictive value of hyponatremia in hospitalized Asian HF patients.
Methods: The Clinical Characteristics and Outcomes in the Relation with Serum Sodium Le..
|
|
|
Gastroenterology / Original Article
Prevalence of and risk factors for endogenous endophthalmitis in patients with pyogenic liver abscesses
In Hyung Park, Chung Hwan Jun, Jin Woo Wi, Seon Young Park, Wan Sik Lee, Sook In Jung, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2015;30(4):453-459. Published online June 29, 2015
Background/Aims: Although pyogenic liver abscesses (PLAs) can be successfully treated, the visual prognosis of patients with endogenous endophthalmitis (EE) associated with a PLA is poor. Early diagnosis and prompt intervention may salvage useful vision. Therefore, we investigated risk factors for E..
|
|
|
Pulmonology / Review
Phenotype of asthma-chronic obstructive pulmonary disease overlap syndrome
Chin Kook Rhee
Korean J Intern Med. 2015;30(4):443-449. Published online June 29, 2015
Many patients with asthma or chronic obstructive pulmonary disease (COPD) have overlapping characteristics of both diseases. By spirometric definition, patients with both fixed airflow obstruction (AO) and bronchodilator reversibility or fixed AO and bronchial hyperresponsiveness can be considered t..
|
|
|
Gastroenterology / Review
A 2015 roadmap for the management of hepatitis C virus infections in Asia
Seng Gee Lim, Yock Young Dan
Korean J Intern Med. 2015;30(4):423-433. Published online June 29, 2015
The prevalence of hepatitis C virus (HCV) in Asia is 0.5% to 4.7%, with three different genotypes predominating, depending on the geographic region: genotype 1b in East Asia, genotype 3 in South and Southeast Asia, and genotype 6 in Indochina. Official approval for direct-acting antiviral agents (DA..
|
|
|
Rheumatology / Original Article
Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population
Chang-Nam Son, Go Choi, So-Yeon Lee, Ji-Min Lee, Tae-Han Lee, Hye-Jin Jeong, Chang-Gyu Jung, Ji-Min Kim, Yong-Won Cho, Sang-Hyon Kim
Korean J Intern Med. 2015;30(3):384-390. Published online April 29, 2015
Background/Aims: The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; and to evaluate the relationship between RA disease activity and sleep quality in Korea.
Methods: A total of 130 RA patients and 67 age- and sex-matched healthy c..
|
|
|
Infectious diseases / Original Article
A comparison of the clinical characteristics of elderly and non-elderly women with community-onset, non-obstructive acute pyelonephritis
U-Im Chang, Hyung Wook Kim, Yong-sun Noh, Seong-Heon Wie
Korean J Intern Med. 2015;30(3):372-383. Published online April 29, 2015
Background/Aims: Acute pyelonephritis (APN) is the most common cause of community-onset bacteremia in hospitalized elderly patients. The objectives of this study were to investigate the differences in the clinical and microbiological data of hospitalized elderly and non-elderly women with community-..
|
|
|
Pulmonology / Original Article
Drug-resistance pattern of Mycobacterium tuberculosis strains from patients with pulmonary and extrapulmonary tuberculosis during 2006 to 2013 in a Korean tertiary medical center
Ho Young Lee, Jin Lee, Young Seok Lee, Mi-Yeong Kim, Hyun-Kyung Lee, Young-Min Lee, Jeong Hwan Shin, Yousang Ko
Korean J Intern Med. 2015;30(3):325-334. Published online April 29, 2015
Background/Aims: We evaluated the trend in the rates of drug-resistant tuberculosis (TB) over time, as well as the difference in the drug-resistance pattern between pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) at a private referral center in South Korea.
Methods: All patients..
|
|
|
Allergy / Original Article
Association of nasal inflammation and lower airway responsiveness in schoolchildren based on an epidemiological survey
Jun-Ho Myung, Hyun-Jeong Seo, Soo-Jeong Park, Bo-Young Kim, Il-Sang Shin, Jun-Hak Jang, Yun-Kyung Kim, An-Soo Jang
Korean J Intern Med. 2015;30(2):226-231. Published online February 27, 2015
Background/Aims: We sought to increase our understanding of the rhinitis-asthma relationship and improve strategies for the treatment of patients with these diseases. The aim of this study was to identify a connection between upper airway inflammation and lower airway responsiveness.
Methods: We co..
|
|
|
Infectious diseases / Original Article
Clinical and microbiological features of Providencia bacteremia: experience at a tertiary care hospital
Hee Kyoung Choi, Young Keun Kim, Hyo Youl Kim, Jeong Eun Park, Young Uh
Korean J Intern Med. 2015;30(2):219-225. Published online February 27, 2015
Background/Aims: Providencia species frequently colonize urinary catheters and cause urinary tract infections (UTIs); however, bacteremia is uncommon and not well understood. We investigated the clinical features of Providencia bacteremia and the antibiotic susceptibility of Provide..
|
|
|
Nephrology / Original Article
Cutoff value of serum procalcitonin as a diagnostic biomarker of infection in end-stage renal disease patients
Wan Soo Lee, Dae Woong Kang, Jong Hun Back, Hyun Lee Kim, Jong Hoon Chung, Byung Chul Shin
Korean J Intern Med. 2015;30(2):198-204. Published online February 27, 2015
Background/Aims: Serum procalcitonin (PCT) levels are low in healthy individuals but are elevated in patients with a serious bacterial infection or sepsis. In this study, we examined the ability of serum PCT concentration to diagnose infections in end-stage renal disease (ESRD) patients, and sought ..
|
|
|
Pulmonology / Original Article
Awareness of chronic obstructive pulmonary disease in current smokers: a nationwide survey
So Yeong Mun, Yong Il Hwang, Joo Hee Kim, Sunghoon Park, Seung Hun Jang, Jae Yong Seo, Ja Kyung Kim, Yong Bum Park, Jae Jung Shim, Ki-Suck Jung
Korean J Intern Med. 2015;30(2):191-197. Published online February 27, 2015
Background/Aims: Cigarette smoking is the most common risk factor for chronic obstructive pulmonary disease (COPD). However, few studies of the attitudes toward COPD of smokers, the group at risk of developing this condition, have been conducted. The purpose of this study was to explore the awarenes..
|
|
|
Cardiology / Original Article
Effect of revascularization strategy in patients with acute myocardial infarction and renal insuf-ficiency with multivessel disease
Hyukjin Park, Young Joon Hong, Si Hyun Rhew, Sung Soo Kim, Young Wook Jeong, Hae Chang Jeong, Jae Yeong Cho, Soo Young Jang, Ki Hong Lee, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Yoon, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park
Korean J Intern Med. 2015;30(2):177-190. Published online February 27, 2015
Background/Aims: The aim of this study was to compare the risk of complications and outcome between infarct-related artery (IRA)-only revascularization and multivessel (MV) revascularization in patients with acute myocardial infarction (MI) with renal insufficiency and MV disease.
Methods: A total ..
|
|
|
Gastroenterology / Review
Roadmap for elimination of gastric cancer in Korea
David Y. Graham
Korean J Intern Med. 2015;30(2):133-139. Published online February 27, 2015
Most gastric cancers are caused by infection with the common human bacterial pathogen, Helicobacter pylori. It is now accepted that gastric cancer can be prevented and virtually eliminated by H. pylori eradication and this knowledge was responsible for country-wide H. pylori era..
|
|
|
Infectious diseases / Original Article
Utilization of the respiratory virus multiplex reverse transcription-polymerase chain reaction test for adult patients at a Korean tertiary care center
Mi Young Ahn, Seong-Ho Choi, Jin-Won Chung, Hye Ryoun Kim
Korean J Intern Med. 2015;30(1):96-103. Published online December 30, 2014
Background/Aims: Respiratory viruses (RVs) are considered to be important respiratory pathogens in adult patients, and the multiplex reverse transcription-polymerase chain reaction (RT-PCR) test is used frequently in adult patients with respiratory infections. However, clinical data regarding utiliz..
|
|
|
Pulmonology / Original Article
Proteomic differences with and without ozone-exposure in a smoking-induced emphysema lung model
Soo-Taek Uh, So-My Koo, An Soo Jang, Sung Woo Park, Jae Sung Choi, Yong-Hoon Kim, Choon Sik Park
Korean J Intern Med. 2015;30(1):62-72. Published online December 30, 2014
Background/Aims: Acute exacerbations in chronic obstructive pulmonary disease may be related to air pollution, of which ozone is an important constituent. In this study, we investigated the protein profiles associated with ozone-induced exacerbations in a smoking-induced emphysema model.
Methods: M..
|
|
|
