|
Pulmonology / Original Article
Bleeding complications in critically ill patients with liver cirrhosis
Jaeyoung Cho, Sun Mi Choi, Su Jong Yu, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Jinwoo Lee
Korean J Intern Med. 2016;31(2):288-295. Published online January 25, 2016
Background/Aims: Patients with liver cirrhosis (LC) are at risk for critical events leading to Intensive Care Unit (ICU) admission. Coagulopathy in cirrhotic patients is complex and can lead to bleeding as well as thrombosis. The aim of this study was to investigate bleeding complications in critica..
|
|
|
Cardiology / Original Article
Angiotensin II type 1 receptor blockers as a first choice in patients with acute myocardial infarction
Jang Hoon Lee, Myung Hwan Bae, Dong Heon Yang, Hun Sik Park, Yongkeun Cho, Won Kee Lee, Myung Ho Jeong, Young Jo Kim, Myeong Chan Cho, Chong Jin Kim, Shung Chull Chae, Korea Acute Myocardial Infarction Registry Investigators
Korean J Intern Med. 2016;31(2):267-276. Published online December 23, 2015
Background/Aims: Angiotensin II type 1 receptor blockers (ARBs) have not been adequately evaluated in patients without left ventricular (LV) dysfunction or heart failure after acute myocardial infarction (AMI).
Methods: Between November 2005 and January 2008, 6,781 patients who were not receiving a..
|
|
|
Letter to the editor
Successful transcatheter closure of an inferior sinus venosus atrial septal defect
Hyung Duk Kim, Moon Sung Kim, Kyung-Jin Yun, Sang Mook Bae, Sung-Ho Her, Jae-Hwan Lee
Korean J Intern Med. 2016;31(1):176-178. Published online December 28, 2015
|
|
|
Infectious diseases / Original Article
Risk factors and etiology of surgical site infection after radical neck dissection in patients with head and neck cancer
So Yeon Park, Mi Suk Kim, Joong Sik Eom, Jin Seo Lee, Young Soo Rho
Korean J Intern Med. 2016;31(1):162-169. Published online December 28, 2015
Background/Aims: Surgical site infection (SSI) is a major complication after radical neck dissection (RND) in patients with head and neck cancer (HNC). We investigated the incidence, risk factors, and etiology of SSI among patients who underwent RND.
Methods: A retrospective cohort study was perfor..
|
|
|
Infectious diseases / Original Article
Amikacin therapy for urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli
Sung-Yeon Cho, Su-Mi Choi, Sun Hee Park, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo
Korean J Intern Med. 2016;31(1):156-161. Published online December 28, 2015
Background/Aims: The number of urinary tract infections (UTIs) caused by extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) is increasing. In an outpatient setting, there are limited therapeutic options to treat ESBL-producing pathogens. We evaluated the outcomes of amikacin..
|
|
|
Hemato-oncology / Original Article
Evaluation of treatment response and tissue necrosis as prognostic indicators following neoadjuvant chemoradiotherapy in rectal cancer patients
Ji-Han Jung, Ho Jung An, Hyung-Jin Kim, Jonghoon Lee, Kang-Moon Lee, Sung Hwan Kim, Hyeon-Min Cho, Byoung Yong Shim
Korean J Intern Med. 2016;31(1):134-144. Published online December 28, 2015
Background/Aims: The objective of this study was to assess the prognostic roles of treatment response and tissue necrosis after chemoradiotherapy (CRT) in locally advanced rectal cancer.
Methods: A total of 243 patients with locally advanced rectal cancer who underwent neoadjuvant CRT were included..
|
|
|
Nephrology / Original Article
Advanced chronic kidney disease: a strong risk factor for Clostridium difficile infection
Sun Chul Kim, Min Young Seo, Jun Yong Lee, Ki Tae Kim, Eunjung Cho, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho, Hyoung-Kyu Kim
Korean J Intern Med. 2016;31(1):125-133. Published online December 28, 2015
Background/Aims: It has been suggested that chronic kidney disease (CKD) is a risk factor for Clostridium difficile infection (CDI) and is associated with increased mortality among patients infected with C. difficile. However, recent studies of the clinical impact of CKD on CDI in Asia..
|
|
|
Nephrology / Original Article
Angiotensin III increases monocyte chemoattractant protein-1 expression in cultured human proximal tubular epithelial cells
Hyung Wook Kim, Young Ok Kim, Sun Ae Yoon, Jeong-Sun Han, Hyun-Bae Chun, Young Soo Kim
Korean J Intern Med. 2016;31(1):116-124. Published online December 28, 2015
Background/Aims: We investigated whether angiotensin III (Ang III) is involved in monocyte recruitment through regulation of the chemokine monocyte chemoattractant protein-1 (MCP-1) in cultured human proximal tubular epithelial cells (HK-2 cells).
Methods: We measured MCP-1 levels in HK-2 cells tha..
|
|
|
Cardiology / Original Article
Predictive value of CHADS2 score for cardiovascular events in patients with acute coronary syndrome and documented coronary artery disease
In Sook Kang, Wook Bum Pyun, Gil Ja Shin
Korean J Intern Med. 2016;31(1):73-81. Published online December 28, 2015
Background/Aims: The CHADS2 score, used to predict the risk of ischemic stroke in atrial fibrillation (AF) patients, has been reported recently to predict ischemic stroke in patients with coronary heart disease, regardless of the presence of AF. However, little data are available regardin..
|
|
|
Gastroenterology / Original Article
New monoclonal antibody-based test for Helicobacter pylori urease in gastric tissue
Do Hyun Kim, Ho Dong Kim, Hyeuk Park, Seung Choi, Jae Won Beom, Woo Jong Kim, Chang Kook Park, Young Jik Lee, Ju Young Park, Hyung Rag Kim, Chul Park, Young Eun Joo, Young Do Jung
Korean J Intern Med. 2016;31(1):40-45. Published online December 28, 2015
Background/Aims: To evaluate a new monoclonal antibody for Helicobacter pylori urease in gastric tissue.
Methods: A total of 107 volunteers were enrolled. All subjects underwent a 13C-urea breath test and esophagogastroduodenoscopy. Gastric aspirates were analyzed for pH and ammon..
|
|
|
Gastroenterology / Review
The antibacterial effect of fatty acids on Helicobacter pylori infection
Sung Woo Jung, Sang Woo Lee
Korean J Intern Med. 2016;31(1):30-35. Published online December 28, 2015
Eradication of Helicobacter pylori is recommended for the management of various gastric diseases, including peptic ulcers and mucosa-associated lymphoid tissue lymphoma. Because of the increasing prevalence of antibiotic resistance, the eradication rates of antibiotic-based therapies have dec..
|
|
|
Cardiology / Review
Breakthrough in heart failure with preserved ejection fraction: are we there yet?
Shir Lynn Lim, Carolyn Su Ping Lam
Korean J Intern Med. 2016;31(1):1-14. Published online December 28, 2015
Heart failure with preserved ejection fraction (HFPEF) is a global health problem of considerable socioeconomic burden. It is projected to worsen with the aging population worldwide. The lack of effective therapies underscores our incomplete understanding of this complex heterogeneous syndrome. A no..
|
|
|
Letter to the editor
Fabry disease previously diagnosed as Henoch-Schonlein purpura
Ji Hyeong Kim, Dong Hoon Han, Moo Yong Park, Soo Jeong Choi, Jin Kuk Kim, Seung Duk Hwang, So Young Jin
Korean J Intern Med. 2015;30(6):925-927. Published online October 30, 2015
|
|
|
Letter to the editor
Acute myocardial infarction caused by a floating thrombus in the proximal ascending aorta
Woong Jeon, Seung-Jin Lee, Sang-Ho Park, Se-Whan Lee, Won-Yong Shin, Dong-Kyu Jin
Korean J Intern Med. 2015;30(6):921-924. Published online October 30, 2015
|
|
|
Infectious diseases / Original Article
Serum galactomannan levels in the diagnosis of invasive aspergillosis
Yildiz Okuturlar, Fahir Ozkalemkas, Beyza Ener, Sibel Ocak Serin, Esra Kazak, Tulay Ozcelik, Vildan Ozkocaman, Hasan Atilla Ozkan, Halis Akalin, Meral Gunaldi, Ridvan Ali
Korean J Intern Med. 2015;30(6):899-905. Published online October 30, 2015
Background/Aims: In this study, the sensitivity-specificity of galactomannan-enzyme immunoassay (GM-EIA) with a cut-off value of 0.5 for a single, two, or three consecutive positivity in the diagnosis of invasive pulmonary aspergillosis (IPA) in neutropenic patients with hematological malignancy was inves..
|
|
|
Hemato-oncology / Original Article
Clinical efficacy of erlotinib, a salvage treatment for non-small cell lung cancer patients following gefitinib failure
Kyoung Min Cho, Bhumsuk Keam, Tae Min Kim, Se-Hoon Lee, Dong-Wan Kim, Dae Seog Heo
Korean J Intern Med. 2015;30(6):891-898. Published online October 30, 2015
Background/Aims: The purpose of this study was to identify predictive factors for erlotinib treatment in non-small cell lung cancer (NSCLC) patients following gefitinib failure.
Methods: Forty-five patients with NSCLC who were treated with erlotinib following gefitinib failure at Seoul National Uni..
|
|
|
Nephrology / Original Article
The effects of nonyl phenoxypolyethoxyl ethanol on cell damage pathway gene expression in SK-NSH cells
Samel Park, Il-woong Hwang, Jin-sheon Kim, Hyo-chul Kang, Su-Yeon Park, Hyo-wook Gil, Ho-yeon Song, Sae-yong Hong
Korean J Intern Med. 2015;30(6):873-883. Published online October 30, 2015
Background/Aims: Most pesticide formulations contain both chief and additive ingredients. But, the additives may not have been tested as thoroughly as the chief ingredients. The surfactant, nonyl phenoxypolyethoxylethanol (NP40), is an additive frequently present in pesticide formulations. We invest..
|
|
|
Nephrology / Original Article
Predicting postoperative total calcium requirements after parathyroidectomy in secondary hyperparathyroidism
Byung Heon Kang, Soon Young Hwang, Jeong Yeop Kim, Yu Ah Hong, Mi Yeon Jung, Eun Ah Lee, Ji Eun Lee, Jae Bok Lee, Gang Jee Ko, Heui Jung Pyo, Young Joo Kwon
Korean J Intern Med. 2015;30(6):856-864. Published online October 30, 2015
Background/Aims: To prevent hypocalcemia after parathyroidectomy (PTX), parenteral calcium is required in addition to oral calcitriol and calcium. After switching to oral calcium, patients can be discharged from the hospital. The aim of this study was to analyze the clinical characteristics and outc..
|
|
|
Endocrinology-metabolism / Original Article
Obstructive sleep apnea with excessive daytime sleepiness is associated with non-alcoholic fatty liver disease regardless of visceral fat
Ji Hee Yu, Jae Hee Ahn, Hye Jin Yoo, Ji A Seo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Chol Shin, Nan Hee Kim
Korean J Intern Med. 2015;30(6):846-855. Published online October 30, 2015
Background/Aims: Obstructive sleep apnea (OSA) is associated with an increased risk of obesity and non-alcoholic fatty liver disease (NAFLD), but it remains unclear whether the risk of NAFLD is independently related to OSA regardless of visceral obesity. Thus, the aim of the present study was to exa..
|
|
|
Cardiology / Original Article
Temporal trends and in-hospital outcomes of primary percutaneous coronary intervention in nonagenarians with ST-segment elevation myocardial infarction
Joon Young Kim, Myung Ho Jeong, Yong Woo Choi, Yong Keun Ahn, Shung Chull Chae, Seung Ho Hur, Taek Jong Hong, Young Jo Kim, In Whan Seong, In Ho Chae, Myeong Chan Cho, Jung Han Yoon, Ki Bae Seung, Other Korea Acute Myocardial Infarction Registry Investigators
Korean J Intern Med. 2015;30(6):821-828. Published online October 30, 2015
Background/Aims: Data regarding the outcomes of primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in nonagenarians are very limited. The aim of the present study was to evaluate the temporal trends and in-hospital outcomes of primary PCI in nonag..
|
|
|
