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Gastroenterology / Original Article
Survey of perinatal hepatitis B virus transmission after Korean National Prevention Program in a tertiary hospital
Jae Hoon Kim, Ju Seung Kim, Jong Joon Lee, Jung Ho Kim, Suk Young Kim, Young Kul Jung, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim
Korean J Intern Med. 2014;29(3):307-314. Published online April 29, 2014
Background/Aims: The Ministry of Health and Welfare and the Korea Centers for Disease Control and Prevention in South Korea have been organizing hepatitis B virus (HBV) vertical infection prevention projects since July 2002. In this single-institute study, the results of surveys conducted in ..
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Pulmonology / Review
Modifiers of TGF-b1 effector function as novel therapeutic targets of pulmonary fibrosis
Chang-Min Lee, Jin Wook Park, Won-Kyung Cho, Yang Zhou, Boram Han, Pyoung Oh Yoon, Jeiwook Chae, Jack A Elias, Chun Geun Lee
Korean J Intern Med. 2014;29(3):281-290. Published online April 29, 2014
Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-b1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs including skin, liver, kidney, and lung. Thus, TGF-b1 and its signaling pathways have been at..
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Nephrology / Original Article
Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis
Ji-Hye Lee, Mee-Hye Oh, Jae-Seok Park, Gyoung-Jae Na, Hye-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2014;29(2):176-182. Published online February 27, 2014
Background/Aims: The purpose of this study was to investigate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 on podocytes in immunoglobulin A (IgA) glomerulonephritis (GN).
Methods: Renal biopsy specimens from 52 IgA G..
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Gastroenterology / Review
Current status of functional dyspepsia in Korea
Hyuk Lee, Hye-Kyung Jung, Kyu Chan Huh, Functional Dyspepsia Study Group in the Korean Society of Neurogastroenterology and Motility
Korean J Intern Med. 2014;29(2):156-165. Published online February 27, 2014
Dyspepsia refers to group of commonly occurring upper gastrointestinal symptoms. The majority of patients with dyspepsia suffer from functional (nonulcer) dyspepsia. Although there is a lack of epidemiological data from population-based or patient cohort studies in Korea, the current understanding o..
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Case Report
Hypothermia-induced acute kidney injury in an
elderly patient
Hyun Ju Yoon, Mun Chul Kim, Jae Woo Park, Min A Yang, Cheon Beom Lee, In O Sun, Kwang Young Lee
Korean J Intern Med. 2014;29(1):111-115. Published online January 2, 2014
Hypothermia, defined as an unintentional decline in the core body temperature
to below 35°C, is a life-threatening condition. Patients with malnutrition and
diabetes mellitus as well as those of advanced age are at high risk for accidental
hypothermia. Due to the high mortality rates of acciden..
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Case Report
Spontaneous coronary artery dissection by
intravascular ultrasound in a patient with
myocardial infarction
Ji Hun Jang, Dae Hyeok Kim, Dong Hyuk Yang, Seong Il Woo, Jun Kwan, Keum Soo Park, Sung-Hee Shin
Korean J Intern Med. 2014;29(1):106-110. Published online January 2, 2014
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome
and sudden cardiac death. The incidence, causes, pathogenesis, and treatment
have not been defined clearly, but spontaneous coronary artery dissection
should be considered in young patients without major cardiovascu..
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Cardiology / Original Article
Long-term outcomes of intravascular
ultrasound-guided implantation of bare metal
stents versus drug-eluting stents in primary
percutaneous coronary intervention
Yun-Kyeong Cho, Seung-Ho Hur, Nam-Hee Park, Sang-Woong Choi, Ji-Hyun Sohn, Hyun-Ok Cho, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Chang-Wook Nam, Yoon-Nyun Kim, Kwon-Bae Kim
Korean J Intern Med. 2014;29(1):66-75. Published online January 2, 2014
Background/Aims: While drug-eluting stents (DESs) have shown favorable outcomes
in ST‑segment elevation myocardial infarction (STEMI) compared to bare
metal stents (BMSs), there are concerns about the risk of stent thrombosis (ST)
with DESs. Because intravascular ultrasound (IVUS) guidance may ..
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Infectious diseases / Original Article
Third-generation cephalosporin resistance of community-onset Escherichia coli and Klebsiella pneumoniae bacteremia in a secondary hospital
Shinwon Lee, Seung Woo Han, Kun Woo Kim, Do young Song, Ki Tae Kwon
Korean J Intern Med. 2014;29(1):49-56. Published online January 2, 2014
Background/Aims: To enable appropriate antimicrobial treatment for community-
onset infections in emergency departments (EDs), data are needed on the
resistance profiles of Escherichia coli and Klebsiella pneumoniae, which are the main
pathogens of community-onset bacteremia.
Methods: Records we..
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Endocrinology-metabolism / Original Article
Measurement of antioxidant capacity using the biological antioxidant potential test and its role as a predictive marker of metabolic syndrome
Jung Hee Kim, Hyun Wook Baik, Yeong Sook Yoon, Hyo Jee Joung, Ju Sang Park, Sang Jong Park, Eun Jeong Jang, Sang Woon Park, Sang Jung Kim, Mi Jeoung Kim, Dong Ok Jeon, Hyo Jin Cho, Sang Jin Lee, Sung Gyu Im, Sun Kyung Jang
Korean J Intern Med. 2014;29(1):31-39. Published online January 2, 2014
Background/Aims: Oxidative stress increases the risk of cardiovascular complications
of metabolic syndrome (MetS). This study was conducted to examine the
difference in antioxidant capacity according to the presence of MetS, and to characterize
the association between antioxidant capacity and Me..
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Letter to the editor
A case of primary aldosteronism presenting as non-ST elevation myocardial infarction
Ja Min Byun, Suk Chon, Soo-Joong Kim
Korean J Intern Med. 2013;28(6):739-742. Published online October 29, 2013
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Perspectives
How far has The Korean Journal of Internal Medicine advanced in terms of journal metrics?
Sun Huh
Korean J Intern Med. 2013;28(6):635-638. Published online October 29, 2013
The Korean Journal of Internal Medicine has already been valued as an international journal, according to a citation analysis in 2011. Now, 2 years later, I would like to confirm how much the Journal has advanced from the point of view of journal metrics by looking at the impact ..
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Endocrinology-metabolism / Original Article
Neuroprotective effects of Vitis vinifera extract on prediabetic mice induced by a high-fat diet
Heung Yong Jin, Youn Soo Cha, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(5):579-586. Published online August 14, 2013
Background/AimsVitis vinifera grape seed extract (VVE) contains oligomeric proanthocyanidins that show antioxidant and free radical-scavenging activities. We evaluated VVE for its neuroprotective effect in prediabetic mice induce by a high-fat diet (HD).
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Gastroenterology / Original Article
Expression of procaspase 3 and activated caspase 3 and its relevance in hormone-responsive gallbladder carcinoma chemotherapy
Sanjeev Kumar Maurya, Mallika Tewari, Bechan Sharma, Hari Shanker Shukla
Korean J Intern Med. 2013;28(5):573-578. Published online August 14, 2013
Background/AimsThe higher incidence of gallbladder cancer (GBC) in females has been accredited to the involvement of hormones. The clinical implications of sex hormone receptors in GBC are well established. Cysteine proteases (such as caspase-3-9, etc.) are known to play a cen..
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Cardiology / Original Article
Impact of family history on the presentation and clinical outcomes of coronary heart disease: data from the Korea Acute Myocardial Infarction Registry
Choongki Kim, Hyuk-Jae Chang, Iksung Cho, Ji Min Sung, Donghoon Choi, Myung Ho Jeong, Yang Soo Jang,
Korean J Intern Med. 2013;28(5):547-556. Published online August 14, 2013
Background/AimsFamily history (FHx) of coronary heart disease (CHD) is a well-known risk factor for CHD. However, the prognostic implication of FHx has not been established clearly in patients with acute myocardial infarction (AMI). MethodsIn t..
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Gastroenterology / Review
Current evidence of effects of Helicobacter pylori eradication on prevention of gastric cancer
Il Ju Choi
Korean J Intern Med. 2013;28(5):525-537. Published online August 14, 2013
Gastric cancer is the second most common cause of cancer death worldwide and is usually detected at a late stage, except in Korea and Japan where early screening is in effect. Results from animal and epidemiological studies suggest that Helicobacter pylori infection, and subseque..
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Gastroenterology / Review
Current status of chemotherapy for the treatment of advanced biliary tract cancer
Takashi Sasaki, Hiroyuki Isayama, Yousuke Nakai, Kazuhiko Koike
Korean J Intern Med. 2013;28(5):515-524. Published online August 14, 2013
Chemotherapy is indispensable for the treatment of advanced biliary tract cancer. Recently, reports regarding first-line chemotherapy have increased, and first-line chemotherapy treatment has become gradually more sophisticated. Gemcitabine and cisplatin combination therapy (or gemcitabine and ox..
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Case Report
A case of fulminant community-acquired Acinetobacter baumannii pneumonia in Korea
Yoon Jung Oh, Sung Heon Song, Seung Hee Baik, Hak Hyun Lee, In Mee Han, Dong Hyun Oh
Korean J Intern Med. 2013;28(4):486-490. Published online July 1, 2013
Acinetobacter baumannii (AB) is a common pathogen found in patients with hospital-acquired pneumonia all over the world. Community-acquired AB pneumonia, however, is very rare and has seldom been reported in Asia-Pacific countries. Community-acquired AB pneumonia has a fulminant ..
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Endocrinology-metabolism / Original Article
Adipokines, insulin-like growth factor binding protein-3 levels, and insulin sensitivity in women with polycystic ovary syndrome
Hyejin Lee, Jee-Young Oh, Yeon-Ah Sung
Korean J Intern Med. 2013;28(4):456-463. Published online July 1, 2013
Background/AimsMany women with polycystic ovary syndrome (PCOS) exhibit insulin resistance. Adipose tissue plays an important role in insulin resistance, and adipokines including tumor necrosis factor (TNF)-α and adiponectin are altered in PCOS. Insulin-like growth factor bin..
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Gastroenterology / Original Article
Factors influencing hepatocellular carcinoma prognosis after hepatectomy: a single-center experience
Sung Keun Park, Young Kul Jung, Dong Hae Chung, Keon Kuk Kim, Yeon Ho Park, Jung Nam Lee, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim
Korean J Intern Med. 2013;28(4):428-438. Published online July 1, 2013
Background/AimsRecurrence after hepatic resection is one of the most important factors impacting the prognosis and survival of patients with hepatocellular carcinoma (HCC). We identified prognostic factors affecting overall survival (OS) and disease-free survival (DFS) in pati..
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