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Rheumatology / Original Article
Resting energy expenditure is not associated with disease activity in women with rheumatoid arthritis: cross-sectional study
Jung-Yoon Choe, Sung-Hoon Park, Hwajeong Lee, Hyun Hee Kwon, Seong-Kyu Kim
Korean J Intern Med. 2014;29(4):516-524. Published online June 27, 2014
Background/Aims: Increased resting energy expenditure (REE) in rheumatoid arthritis (RA) patients is thought to be caused by hypermetabolism associated with production of proinflammatory cytokines. Our aim in the present study was to explore the possible association between REE and disease activity ..
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Nephrology / Original Article
Ferritin as a predictor of decline in residual renal function in peritoneal dialysis patients
Soon Mi Hur, Hye Young Ju, Moo Yong Park, Soo Jeong Choi, Jin Kuk Kim, Seung Duk Hwang
Korean J Intern Med. 2014;29(4):489-497. Published online June 27, 2014
Background/Aims: Inflammation is an important factor in renal injury. Ferritin, an inflammatory marker, is considered an independent predictor of rapid renal progression in patients with chronic kidney disease. However, the relationship between ferritin and residual renal function (RRF) in patients ..
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Endocrinology-metabolism / Original Article
The effect of 5-aminoimidazole-4-carboxamideribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells
Won Gu Kim, Hyun-Jeung Choi, Tae Yong Kim, Young Kee Shong, Won Bae Kim
Korean J Intern Med. 2014;29(4):474-481. Published online June 27, 2014
Background/Aims: 5′-Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a cellular energy sensor that monitors intracellular AMP/adenosine triphosphate (ATP) ratios and is a key regulator of the proliferation and survival of diverse malignant cell types. In the present study, we inves..
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Pulmonology / Original Article
Prevalence and risk factors for reflux esophagitis in patients with chronic obstructive pulmonary disease
Seo Woo Kim, Jin Hwa Lee, Yun Su Sim, Yon Ju Ryu, Jung Hyun Chang
Korean J Intern Med. 2014;29(4):466-473. Published online June 27, 2014
Background/Aims: Gastroesophageal reflux disease is one of the most common causes of chronic cough and is a potential risk factor for the exacerbation of chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the prevalence and risk factors for reflux esophagitis (RE)..
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Cardiology / Original Article
Prediction of infarct severity from triiodothyronine levels in patients with ST-elevation myocardial infarction
Dong Hun Kim, Dong-Hyun Choi, Hyun-Wook Kim, Seo-Won Choi, Bo-Bae Kim, Joong-Wha Chung, Young-Youp Koh, Kyong-Sig Chang, Soon-Pyo Hong
Korean J Intern Med. 2014;29(4):454-465. Published online June 27, 2014
Background/Aims: The aim of the present study was to evaluate the relationship between thyroid hormone levels and infarct severity in patients with ST-elevation myocardial infarction (STEMI).
Methods: We retrospectively reviewed thyroid hormone levels, infarct severity, and the extent of transmura..
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Letter to the editor
Native valve endocarditis due to extended spectrum β-lactamase producingKlebsiella pneumoniae
Hyun-Ae Jung, Young Eun Ha, Damin Kim, Jihyun Park, Cheol-In Kang, Doo Ryeon Chung, Seung Woo Park, Ki Ik Sung, Jae-Hoon Song, Kyong Ran Peck
Korean J Intern Med. 2014;29(3):398-401. Published online April 29, 2014
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Nephrology / Original Article
Urinary excretion of β2-microglobulin as a prognostic marker in immunoglobulin A nephropathy
Jae Ryung Shin, Seung Min Kim, Jung Sun Yoo, Ji Yoon Park, Seul Ki Kim, Joo Hee Cho, Kyung Hwan Jeong, Tae Won Lee, Chun Gyoo Ihm
Korean J Intern Med. 2014;29(3):334-340. Published online April 29, 2014
Background/Aims: β2-microglobulin (β2-MG) is freely filtered at the glomerulus and subsequently reabsorbed and catabolized by proximal renal tubular cells. Urinary β2-MG is an early and sensitive biomarker of acute kidney injury; however, its utility as a bio..
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Gastroenterology / Original Article
Survey of perinatal hepatitis B virus transmission after Korean National Prevention Program in a tertiary hospital
Jae Hoon Kim, Ju Seung Kim, Jong Joon Lee, Jung Ho Kim, Suk Young Kim, Young Kul Jung, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim
Korean J Intern Med. 2014;29(3):307-314. Published online April 29, 2014
Background/Aims: The Ministry of Health and Welfare and the Korea Centers for Disease Control and Prevention in South Korea have been organizing hepatitis B virus (HBV) vertical infection prevention projects since July 2002. In this single-institute study, the results of surveys conducted in ..
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Pulmonology / Review
Modifiers of TGF-b1 effector function as novel therapeutic targets of pulmonary fibrosis
Chang-Min Lee, Jin Wook Park, Won-Kyung Cho, Yang Zhou, Boram Han, Pyoung Oh Yoon, Jeiwook Chae, Jack A Elias, Chun Geun Lee
Korean J Intern Med. 2014;29(3):281-290. Published online April 29, 2014
Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-b1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs including skin, liver, kidney, and lung. Thus, TGF-b1 and its signaling pathways have been at..
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Nephrology / Original Article
Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis
Ji-Hye Lee, Mee-Hye Oh, Jae-Seok Park, Gyoung-Jae Na, Hye-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2014;29(2):176-182. Published online February 27, 2014
Background/Aims: The purpose of this study was to investigate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 on podocytes in immunoglobulin A (IgA) glomerulonephritis (GN).
Methods: Renal biopsy specimens from 52 IgA G..
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Gastroenterology / Review
Current status of functional dyspepsia in Korea
Hyuk Lee, Hye-Kyung Jung, Kyu Chan Huh, Functional Dyspepsia Study Group in the Korean Society of Neurogastroenterology and Motility
Korean J Intern Med. 2014;29(2):156-165. Published online February 27, 2014
Dyspepsia refers to group of commonly occurring upper gastrointestinal symptoms. The majority of patients with dyspepsia suffer from functional (nonulcer) dyspepsia. Although there is a lack of epidemiological data from population-based or patient cohort studies in Korea, the current understanding o..
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Case Report
Hypothermia-induced acute kidney injury in an
elderly patient
Hyun Ju Yoon, Mun Chul Kim, Jae Woo Park, Min A Yang, Cheon Beom Lee, In O Sun, Kwang Young Lee
Korean J Intern Med. 2014;29(1):111-115. Published online January 2, 2014
Hypothermia, defined as an unintentional decline in the core body temperature
to below 35°C, is a life-threatening condition. Patients with malnutrition and
diabetes mellitus as well as those of advanced age are at high risk for accidental
hypothermia. Due to the high mortality rates of acciden..
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Case Report
Spontaneous coronary artery dissection by
intravascular ultrasound in a patient with
myocardial infarction
Ji Hun Jang, Dae Hyeok Kim, Dong Hyuk Yang, Seong Il Woo, Jun Kwan, Keum Soo Park, Sung-Hee Shin
Korean J Intern Med. 2014;29(1):106-110. Published online January 2, 2014
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome
and sudden cardiac death. The incidence, causes, pathogenesis, and treatment
have not been defined clearly, but spontaneous coronary artery dissection
should be considered in young patients without major cardiovascu..
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Cardiology / Original Article
Long-term outcomes of intravascular
ultrasound-guided implantation of bare metal
stents versus drug-eluting stents in primary
percutaneous coronary intervention
Yun-Kyeong Cho, Seung-Ho Hur, Nam-Hee Park, Sang-Woong Choi, Ji-Hyun Sohn, Hyun-Ok Cho, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Chang-Wook Nam, Yoon-Nyun Kim, Kwon-Bae Kim
Korean J Intern Med. 2014;29(1):66-75. Published online January 2, 2014
Background/Aims: While drug-eluting stents (DESs) have shown favorable outcomes
in ST‑segment elevation myocardial infarction (STEMI) compared to bare
metal stents (BMSs), there are concerns about the risk of stent thrombosis (ST)
with DESs. Because intravascular ultrasound (IVUS) guidance may ..
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Infectious diseases / Original Article
Third-generation cephalosporin resistance of community-onset Escherichia coli and Klebsiella pneumoniae bacteremia in a secondary hospital
Shinwon Lee, Seung Woo Han, Kun Woo Kim, Do young Song, Ki Tae Kwon
Korean J Intern Med. 2014;29(1):49-56. Published online January 2, 2014
Background/Aims: To enable appropriate antimicrobial treatment for community-
onset infections in emergency departments (EDs), data are needed on the
resistance profiles of Escherichia coli and Klebsiella pneumoniae, which are the main
pathogens of community-onset bacteremia.
Methods: Records we..
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Endocrinology-metabolism / Original Article
Measurement of antioxidant capacity using the biological antioxidant potential test and its role as a predictive marker of metabolic syndrome
Jung Hee Kim, Hyun Wook Baik, Yeong Sook Yoon, Hyo Jee Joung, Ju Sang Park, Sang Jong Park, Eun Jeong Jang, Sang Woon Park, Sang Jung Kim, Mi Jeoung Kim, Dong Ok Jeon, Hyo Jin Cho, Sang Jin Lee, Sung Gyu Im, Sun Kyung Jang
Korean J Intern Med. 2014;29(1):31-39. Published online January 2, 2014
Background/Aims: Oxidative stress increases the risk of cardiovascular complications
of metabolic syndrome (MetS). This study was conducted to examine the
difference in antioxidant capacity according to the presence of MetS, and to characterize
the association between antioxidant capacity and Me..
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Letter to the editor
A case of primary aldosteronism presenting as non-ST elevation myocardial infarction
Ja Min Byun, Suk Chon, Soo-Joong Kim
Korean J Intern Med. 2013;28(6):739-742. Published online October 29, 2013
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Perspectives
How far has The Korean Journal of Internal Medicine advanced in terms of journal metrics?
Sun Huh
Korean J Intern Med. 2013;28(6):635-638. Published online October 29, 2013
The Korean Journal of Internal Medicine has already been valued as an international journal, according to a citation analysis in 2011. Now, 2 years later, I would like to confirm how much the Journal has advanced from the point of view of journal metrics by looking at the impact ..
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Endocrinology-metabolism / Original Article
Neuroprotective effects of Vitis vinifera extract on prediabetic mice induced by a high-fat diet
Heung Yong Jin, Youn Soo Cha, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2013;28(5):579-586. Published online August 14, 2013
Background/AimsVitis vinifera grape seed extract (VVE) contains oligomeric proanthocyanidins that show antioxidant and free radical-scavenging activities. We evaluated VVE for its neuroprotective effect in prediabetic mice induce by a high-fat diet (HD).
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