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Nephrology / Original Article
Mortality prediction of serum neutrophil gelatinase-associated lipocalin in patients requiring continuous renal replacement therapy
Yohan Park, Tae Hyun Ban, Hyung Duk Kim, Eun Jeong Ko, Jongmin Lee, Seok Chan Kim, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim, Byung Ha Chung
Korean J Intern Med. 2021;36(2):392-400. Published online July 7, 2020
Background/Aims: We investigated whether serum neutrophil gelatinase-associated lipocalin (NGAL) can predict mortality in patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT).
Methods: This study enrolled 169 patients who underwent serum NGAL testing at CRRT..
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Review
Recent advances in the management of difficult bile-duct stones: a focus on single-operator cholangioscopy-guided lithotripsy
Chi Hyuk Oh, Seok Ho Dong
Korean J Intern Med. 2021;36(2):235-246. Published online December 1, 2020
The most effective and the standard treatment for bile duct stones (BDSs) is endoscopic retrograde cholangiopancreatography (ERCP). However, in 10% to 15% of patients with BDSs, the stones cannot be removed by conventional ERCP, which involves endoscopic sphincterotomy followed by balloon or basket ..
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Hemato-oncology / Original Article
Treatment outcome and prognostic factors of Korean patients with chronic lymphocytic leukemia: a multicenter retrospective study
Yunsuk Choi, Jung-Hee Lee, Chul Won Jung, Jae-Cheol Jo, Jin Seok Kim, Inho Kim, Silvia Park, June-won Cheong, Sang-Hyuk Park, Sung-Yong Kim, Hong-Ghi Lee
Korean J Intern Med. 2021;36(1):194-204. Published online April 14, 2020
Background/Aims: Compared with Western countries, chronic lymphocytic leukemia (CLL) rarely occurs in Asia and has different clinical characteristics. Thus, we aimed to evaluate the clinical characteristics, treatment outcomes, and prognostic significance of Korean patients with CLL.
Methods: We re..
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Nephrology / Original Article
Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients
Hyunjoo Bae, Do Hyun Na, Ji-Yeun Chang, Ki Hyun Park, Ji Won Min, Eun Jeong Ko, Hyeyoung Lee, Chul Woo Yang, Byung Ha Chung, Eun-Jee Oh
Korean J Intern Med. 2021;36(1):164-174. Published online April 3, 2020
Background/Aims: To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods: We included 68 KTRs with different viremia status (no virem..
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Review
Gallstone pancreatitis: general clinical approach and the role of endoscopic retrograde cholangiopancreatography
Shanker Kundumadam, Evan L. Fogel, Mark Andrew Gromski
Korean J Intern Med. 2021;36(1):25-31. Published online January 1, 2021
Gallstones account for majority of acute pancreatitis in the Western world. Increase in number and smaller size of the stones increases the risk for biliary pancreatitis. In addition to features of acute pancreatitis, these patients also have cholestatic clinical picture. Fluid therapy and enteral n..
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Rheumatology / Original Article
Pilot study: asymptomatic hyperuricemia patients with obesity and nonalcoholic fatty liver disease have increased risk of double contour sign
Hong Ki Min, Hyonjoung Cho, Sung-Hwan Park
Korean J Intern Med. 2020;35(6):1517-1523. Published online June 13, 2019
Background/Aims: Double contour sign (DCS) is a representative ultrasonographic finding in gout. DCS is evidence of monosodium urate deposit in gouty arthritis and has been identified in some patients with asymptomatic hyperuricemia. However, the specific characteristics of asymptomatic hyperuricemi..
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Gastroenterology / Original Article
Effect of calcineurin inhibitor on post-endoscopic retrograde cholangiopancreatography pancreatitis in patients with liver transplantation: a propensity-matched cohort study
Hyoung-Chul Oh, Jeffrey J. Easler, Ihab I. El Hajj, James Watkins, Evan L. Fogel, Lee McHenry, Stuart Sherman, Hyun Kang, Glen A. Lehman
Korean J Intern Med. 2020;35(6):1364-1370. Published online February 19, 2020
Background/Aims: A calcineurin inhibitor may alter pancreatic function and inflammatory reaction. This study aimed to determine the possible pharmacologic effect of the calcineurin inhibitor, tacrolimus, on pancreatic function, and to determine its preventive effect on post-endoscopic retrograde cho..
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Gastroenterology / Original Article
Correlation of the grade of hepatic steatosis between controlled attenuation parameter and ultrasound in patients with fatty liver: a multi-center retrospective cohort study
Jeong-Ju Yoo, Yang Jae Yoo, Woo Ram Moon, Seung Up Kim, Soung Won Jeong, Ha Na Park, Min Gyu Park, Jae Young Jang, Su Yeon Park, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Sang Gyune Kim, Young Seok Kim, Ji Hoon Kim, Jong Eun Yeon, Kwan Soo Byun
Korean J Intern Med. 2020;35(6):1346-1353. Published online November 8, 2019
Background/Aims: The controlled attenuation parameter (CAP), based on transient elastography, is widely used for noninvasive assessment of the degree of hepatic steatosis (HS). We investigated the correlation of the degree HS between CAP and ultrasound (US) in patients with HS.
Methods: In total, 9..
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Gastroenterology / Original Article
Continuous infusion versus intermittent bolus injection of propofol during endoscopic retrograde cholangiopancreatography
Jae Gon Lee, Kyo-Sang Yoo, Young Jae Byun
Korean J Intern Med. 2020;35(6):1338-1345. Published online March 5, 2020
Background/Aims: It is unclear whether continuous infusion or intermittent bolus injection of propofol is better for achieving adequate sedation in endoscopic retrograde cholangiopancreatography (ERCP). We aimed to compare the efficacy and safety of continuous infusion and intermittent bolus injecti..
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Rheumatology / Original Article
Hourly wages of physicians within medical fees based on the Korean relative value unit system
Hyun Ah Kim, Sung Hoon Jung, In Young Park, Seong Hun Kang
Korean J Intern Med. 2020;35(5):1238-1244. Published online December 26, 2019
Background/Aims: It is difficult to reach a social agreement on the appropriate level of compensation for professionals. This study was performed to examine the physician fee embedded in the relative value unit (RVU) system in comparison with the Korean hourly minimum wage.
Methods: The Health Insu..
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Nephrology / Original Article
Current findings of kidney biopsy including nephropathy associated with hypertension and diabetes mellitus in Korea
Kipyo Kim, Sang Ho Lee, Sung Woo Lee, Jung Pyo Lee, Ho Jun Chin; on behalf of the Korean GlomeruloNEphritis sTudy (KoGNET) Group
Korean J Intern Med. 2020;35(5):1173-1187. Published online August 14, 2020
Background/Aims: This study aimed to investigate long-term temporal trends and outcomes of biopsy-proven kidney diseases in a multicenter kidney biopsy cohort, focusing on hypertension and diabetes, the leading causes of end-stage kidney disease (ESKD).
Methods: The study included a total of 21,426..
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Cardiology / Original Article
Differential efficacy between stenting and plain balloon angioplasty for femoropopliteal disease with or without total occlusion
In-Ho Chae, Chang-Hwan Yoon, Young-Guk Ko, Pil-Ki Min, Jae-Hwan Lee, Cheol Woong Yu, Seung Whan Lee, Sang-Rok Lee, Seung Hyuk Choi, Yoon Seok Koh, Donghoon Choi; the K-VIS investigators
Korean J Intern Med. 2020;35(5):1114-1124. Published online February 24, 2020
Background/Aims: Whether the presence of chronic total occlusion (CTO) affects patency after stenting in femoropopliteal lesions is unknown. We determined the effects of plain balloon angioplasty (POBA) in comparison with those of stenting on patency for femoropopliteal CTO and stenosis (non-CTO).
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Gastroenterology / Original Article
Impact of early anti-TNF use on clinical outcomes in Crohn’s disease: a nationwide population-based study
Yoon Suk Jung, Minkyung Han, Sohee Park, Jae Hee Cheon
Korean J Intern Med. 2020;35(5):1104-1113. Published online April 21, 2020
Background/Aims: The optimal timing for initiation of anti-tumor necrosis factor (TNF) therapy in Crohn’s disease (CD) is still debated. Little is known about the clinical outcomes of early versus late administration of anti-TNF agents, especially in Asian CD patients. We aimed to evaluate the imp..
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Allergy / Original Article
Serum potential biomarkers according to sputum inflammatory cell profiles in adult asthmatics
Gyu-Young Hur, Young-Min Ye, Eunmi Yang, Hae-Sim Park
Korean J Intern Med. 2020;35(4):988-997. Published online November 15, 2019
Background/Aims: Asthma is not a single disease but, rather, a heterogeneous inf lammatory disorder with various pathogenic mechanisms. We analyzed the associations between the cellular profile of sputum and the serum levels of inflammatory mediators/cytokines in a cohort of adult asthmatics.
Metho..
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Hemato-oncology / Original Article
Asian variant of intravascular large B-cell lymphoma: a comparison of clinical features based on involvement of the central nervous system
Sang Eun Yoon, Won Seog Kim, Seok Jin Kim
Korean J Intern Med. 2020;35(4):946-956. Published online November 25, 2019
Background/Aims: There are limited data about the influence of the central nervous system (CNS) involvement on the prognosis for patients with the Asian variant of intravascular large B-cell lymphoma (IVLBCL).
Methods: We analyzed 46 patients who were diagnosed with IVLBCL between 2001 and 2018. Al..
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Pulmonology / Original Article
The effect of susceptibility variants, identified in never-smoking female lung cancer cases, on male smokers
Seung Soo Yoo, Hyo-Gyoung Kang, Jin Eun Choi, Mi Jeong Hong, Sook Kyung Do, Jang Hyuck Lee, Won Kee Lee, Shin Yup Lee, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Eung Bae Lee, Jae Yong Park
Korean J Intern Med. 2020;35(4):929-935. Published online December 30, 2019
Background/Aims: Genome wide and candidate gene association studies have identified polymorphisms associated with the risk of lung cancer in never-smokers. This study was conducted to evaluate the association between 11 polymorphisms identified in female never smokers and the lung cancer risk in mal..
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Review
Distinct functions of eosinophils in severe asthma with type 2 phenotype: clinical implications
Youngwoo Choi, Soyoon Sim, Hae-Sim Park
Korean J Intern Med. 2020;35(4):823-833. Published online May 29, 2020
Asthma is commonly recognized as a heterogeneous condition with a complex pathophysiology. With advances in the development of multiple medications for patients with asthma, most asthma symptoms are well managed. Nevertheless, 5% to 10% of adult asthmatic patients (called severe asthma) are in uncon..
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Original Article / Brief Communication
Lung ultrasound for early diagnosis and severity assessment of pneumonia in patients with coronavirus disease 2019
[corrected-article]
Young-Jae Cho, Kyoung-Ho Song, Yunghee Lee, Joo Heung Yoon, Ji Young Park, Jongtak Jung, Sung Yoon Lim, Hyunju Lee, Ho Il Yoon, Kyoung Un Park, Hong Bin Kim, Eu Suk Kim
Korean J Intern Med. 2020;35(4):771-781. Published online July 1, 2020
Background/Aims: Current evidence supports lung ultrasound as a point-ofcare alternative diagnostic tool for various respiratory diseases. We sought to determine the utility of lung ultrasound for early detection of pneumonia and for assessment of respiratory failure among patients with coronavirus ..
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Guideline / Brief Communication
Consensus statement on coronary intervention during the coronavirus disease 19 pandemic: from the Korean Society of Interventional Cardiology
Kwan Yong Lee, Bong-Ki Lee, Won-Jang Kim, Se Hun Kang, Taek Kyu Park, Song-Yi Kim, Jung-Won Suh, Chang-Hwan Yoon, Dong Heon Yang, Sung Kee Ryu, Sang-Hyun Kim, Sung Yun Lee, In-Ho Chae; The Korean Society of Interventional Cardiology COVID-19 Task Force Team
Korean J Intern Med. 2020;35(4):749-757. Published online July 1, 2020
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the novel virus severe acute respiratory syndrome coronavirus 2. The first case developed in December, 2019 in Wuhan, China; several months later, COVID-19 has become pandemic, and there is no end in sight. This disaster is..
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Rheumatology / Original Article
Liver enzyme elevation in patients with ankylosing spondylitis treated with tumor necrosis factor inhibitors: a single-center historical cohort study
Su Jin Choi, Ji Seon Oh, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Korean J Intern Med. 2020;35(3):723-731. Published online December 26, 2019
Background/Aims: Tumor necrosis factor inhibitors (TNFi) have been known to induce liver enzyme elevation, sometimes associated with viral reactivation or toxic hepatitis. We evaluated the incidence and risk factors of TNFi-associated liver enzyme elevation in Korean ankylosing spondylitis (AS) pati..
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