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Pulmonology / Original Article
Clinical characteristics of nursing home-acquired pneumonia in elderly patients admitted to a Korean teaching hospital
Seong Joo Koh, Jong Hoo Lee
Korean J Intern Med. 2015;30(5):638-647. Published online August 27, 2015
Background/Aims: Nursing home-acquired pneumonia (NHAP) is included under healthcare-associated pneumonia. However, the optimal treatment strategy for NHAP has been controversial in several studies. We evaluated the clinical features of NHAP compared to community-acquired pneumonia (CAP) in elderly ..
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Pulmonology / Original Article
Chronic obstructive pulmonary disease (COPD) assessment test scores corresponding to modified Medical Research Council grades among COPD patients
Chang-Hoon Lee, Jinwoo Lee, Young Sik Park, Sang-Min Lee, Jae-Joon Yim, Young Whan Kim, Sung Koo Han, Chul-Gyu Yoo
Korean J Intern Med. 2015;30(5):629-637. Published online August 27, 2015
Background/Aims: In assigning patients with chronic obstructive pulmonary disease (COPD) to subgroups according to the updated guidelines of the Global Initiative for Chronic Obstructive Lung Disease, discrepancies have been noted between the COPD assessment test (CAT) criteria and modified Medical ..
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Cardiology / Original Article
A pharmacodynamic study of the optimal P2Y12 inhibitor regimen for East Asian patients with acute coronary syndrome
Ji Hyun Lee, Sung Gyun Ahn, Bonil Park, Sang Wook Park, Yong Seok Kang, Jun-Won Lee, Young Jin Youn, Min-Soo Ahn, Jang-Young Kim, Byung-Su Yoo, Seung-Hwan Lee, Junghan Yoon
Korean J Intern Med. 2015;30(5):620-628. Published online August 27, 2015
Background/Aims: Newer P2Y12 inhibitors, such as prasugrel and ticagrelor, have greater antiplatelet efficacy but may increase the risk of bleeding. In this study, we compared the pharmacodynamic efficacy of prasugrel and ticagrelor in East Asian patients with acute coronary syndrome (ACS..
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Cardiology / Original Article
Discordance between ambulatory versus clinic blood pressure according to global cardiovascular risk group
Jinho Shin, Sung Ha Park, Ju Han Kim, Sang Hyun Ihm, Kwang-il Kim, Woo Shik Kim, Wook Bum Pyun, Yu-Mi Kim, Sung-il Choi, Soon Kil Kim
Korean J Intern Med. 2015;30(5):610-619. Published online August 27, 2015
Background/Aims: The detection of white coat hypertension (WCH), treated normalized hypertension, and masked hypertension (MH) is important to improve the effectiveness of hypertension management. However, whether global cardiovascular risk (GCR) profile has any effect on the discordance between amb..
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Gastroenterology / Original Article
Oral udenafil and aceclofenac for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a randomized multicenter study
Tae Yoon Lee, Jung Sik Choi, Hyoung-Chul Oh, Tae Jun Song, Jae Hyuk Do, Young Koog Cheon
Korean J Intern Med. 2015;30(5):602-609. Published online August 27, 2015
Background/Aims: Acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography (ERCP). Combination therapy w ith ora l udenafil and aceclofenac may reduce the occurrence of post-ERCP pancreatitis by targeting different pathophysiological mechanisms. We investigated wh..
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Gastroenterology / Original Article
Can proton pump inhibitors reduce rebleeding following Histoacryl sclerotherapy for gastric variceal hemorrhage?
Ka Rham Kim, Chung Hwan Jun, Kyu Man Cho, Jin Woo Wi, Seon Young Park, Sung Bum Cho, Wan Sik Lee, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2015;30(5):593-601. Published online August 27, 2015
Background/Aims: To evaluate the efficacy of proton pump inhibitors (PPIs) in reducing rebleeding and bleeding-related death rates after endoscopic gastric variceal obliteration (GVO) using N-butyl-2-cyanoacrylate (NBC).
Methods: This study enrolled 341 patients who were consecutively diagnosed wi..
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Editorial
Detecting masked high blood pressure in high-risk patients
Hyungseop Kim
Korean J Intern Med. 2015;30(5):590-592. Published online August 27, 2015
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Gastroenterology / Review
Mesenchymal stem cell therapy for liver fibrosis
Young Woo Eom, Kwang Yong Shim, Soon Koo Baik
Korean J Intern Med. 2015;30(5):580-589. Published online August 27, 2015
Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation; however, transplantation is limited by a shortage of donor organs, surgical complications, immunological rejection, and high medical costs. Recently, mesenchymal stem cell (MSC) therapy has been suggested ..
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Gastroenterology / Review
Evidence for beneficial effects of vitamin E
Etsuo Niki
Korean J Intern Med. 2015;30(5):571-579. Published online August 27, 2015
Oxidative stress and lipid peroxidation have been implicated in the pathogenesis of various diseases, including atherosclerosis and fatty liver diseases, and consequently the role of antioxidants in the prevention and treatment of such diseases has received much attention. In particular, the effects..
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Gastroenterology / Review
A systematic approach for the diagnosis and treatment of idiopathic peptic ulcers
Chen-Shuan Chung, Tsung-Hsien Chiang, Yi-Chia Lee
Korean J Intern Med. 2015;30(5):559-570. Published online August 27, 2015
An idiopathic peptic ulcer is defined as an ulcer with unknown cause or an ulcer that appears to arise spontaneously. The first step in treatment is to exclude common possible causes, including Helicobacter pylori infection, infection with other pathogens, ulcerogenic drugs, and uncommon dise..
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Endocrinology-metabolism / Image of interest
Importance of careful Tc-MIBI interpretation in patients with thyroid cancer and primary hyperparathyroidism
Kyung Ae Lee, Heung Yong Jin, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2015;30(4):556-557. Published online June 29, 2015
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Gastroenterology / Image of interest
Hepatic hydatid cyst
[retracted-article]
Keum Nahn Jee
Korean J Intern Med. 2015;30(4):554-555. Published online June 29, 2015
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Hemato-oncology / Letter to the editor
Imatinib mesylate-induced interstitial lung disease in a patient with prior history of Mycobacterium tuberculosis infection
Na-Ri Lee, Ji Won Jang, Hee Sun Kim, Ho-Young Yhim
Korean J Intern Med. 2015;30(4):550-553. Published online June 29, 2015
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Hemato-oncology / Letter to the editor
Metastatic sarcomatoid carcinoma presenting as a pedunculated mass on the floor of the mouth
Ki-Bum Won, Jun-Hwa Song, Jeung-Woo Lee, Won-Chul Ha, Keon-Uk Park
Korean J Intern Med. 2015;30(4):547-549. Published online June 29, 2015
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Endocrinology-metabolism / Letter to the editor
Fatal ischemic stroke in a case of progressive moyamoya vasculopathy associated with uncontrolled thyrotoxicosis
Bon D. Ku, Key-Chung Park, Sung Sang Yoon
Korean J Intern Med. 2015;30(4):543-546. Published online June 29, 2015
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Cardiology / Letter to the editor
Type 2 myocardial infarction after ingestion of mad honey in a patient with normal coronary arteries
Turgut Karabag, Rasit Sayın, Nesimi Yavuz, Ziyaeddin Aktop
Korean J Intern Med. 2015;30(4):540-542. Published online June 29, 2015
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Gastroenterology / Letter to the editor
Extramedullary relapse of multiple myeloma presenting as massive upper gastrointestinal bleeding: a rare complication
Bulent Yasar, Pembegul Gunes, Ozgur Guler, Selma Yagcı, Dilek Benek
Korean J Intern Med. 2015;30(4):538-539. Published online June 29, 2015
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Rheumatology / Original Article
Quantitative analysis of nailfold capillary morphology in patients with fibromyalgia
Dug-Hyun Choi, Hyun-Sook Kim
Korean J Intern Med. 2015;30(4):531-537. Published online June 29, 2015
Background/Aims: Nailfold capillaroscopy (NFC) has been used to examine morphological and functional microcirculation changes in connective tissue diseases. It has been demonstrated that NFC patterns reflect abnormal microvascular dynamics, which may play a role in fibromyalgia (FM) syndrome. The ai..
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Rheumatology / Original Article
Allopurinol hypersensitivity syndrome in patients with hematological malignancies: characteristics and clinical outcomes
Hong Ki Min, Boin Lee, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Young Min Park, Sung-Hwan Park
Korean J Intern Med. 2015;30(4):521-530. Published online June 29, 2015
Background/Aims: Allopurinol is a urate-lowering agent that is commonly used to prevent chemotherapy-related hyperuricemia. Allopurinol hypersensitivity syndrome (AHS) is a disorder involving multiple organs, which may be accompanied by cutaneous adverse reactions. We identified the characteristics ..
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Infectious diseases / Original Article
Drug utilization review of mupirocin ointment in a Korean university-affiliated hospital
Sung Hee Youn, Seung Soon Lee, Sukyeon Kim, Jeong-a Lee, Bum Joon Kim, Jounghee Kim, Hye-kyung Han, Jae-Seok Kim
Korean J Intern Med. 2015;30(4):515-520. Published online June 29, 2015
Background/Aims: Intranasa l mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an over-the-counter drug..
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