| Editorials |
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The underestimated significance of nonproliferative lupus nephritis
Seung-Ki Kwok
Korean J Intern Med. 2023;38(5):581-582. Published online September 1, 2023
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| Reviews |
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Low-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation
Ki Hong Lee, Hyung Wook Park
Korean J Intern Med. 2023;38(5):583-594. Published online September 1, 2023
In the last decade, non-vitamin K antagonist oral anticoagulants (NOACs), a new generation of OACs, were introduced to prevent thromboembolism in patients with atrial fibrillation. Although vitamin K-dependent anticoagulants have long been used as OACs, their inherent disadvantage of considerable bl..
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Optimization of guideline-directed medical treatment for heart failure patients with reduced ejection fraction
Minjung Bak, Jin-Oh Choi
Korean J Intern Med. 2023;38(5):595-606. Published online September 1, 2023
With the increasing number of medications demonstrating mortality benefits in heart failure with reduced ejection fraction (HFrEF), the pharmacological treatment of HFrEF is entering a new phase. To enhance outcomes in heart failure patients through medical treatment, the choice of appropriate medic..
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Role of cardiac imaging in management of heart failure
So Ree Kim, Seong-Mi Park
Korean J Intern Med. 2023;38(5):607-619. Published online August 29, 2023
The significant advancement in cardiac imaging in recent years led to improved diagnostic accuracy in identifying the specific causes of heart failure and also provided physicians with guidelines for appropriately managing patients with heart failure. Diseases that were once considered rare are now ..
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| Guidelines |
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Korean treatment recommendations for patients with axial spondyloarthritis
[corrected-article]
Mi Ryoung Seo, Jina Yeo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Seong-Ryul Kwon, Seong-Kyu Kim, Tae-Jong Kim, Tae-Hwan Kim, Hye Won Kim, Min-Chan Park, Kichul Shin, Sang-Hoon Lee, Eun Young Lee, Hoon Suk Cha, Seung Cheol Shim, Youngim Yoon, Seung Ho Lee, Jun Hong Lim, Han Joo Baek; on behalf of the Korean Society of Spondyloarthritis Research
Korean J Intern Med. 2023;38(5):620-640. Published online July 24, 2023
We aimed to develop evidence-based recommendations for treating axial spondylarthritis (axSpA) in Korea. The development committee was constructed, key clinical questions were determined, and the evidence was searched through online databases including MEDLINE, Embase, Cochrane, KoreaMed, and Kmbase..
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Korean guidelines for the management of gout
Jennifer Jooha Lee, Ji Soo Lee, Min Kyung Chung, Joong Kyong Ahn, Hyo-Jin Choi, Seung-Jae Hong, Chong-Hyeon Yoon, Su-Hyun Kim, Kyung-Hwan Jeong, Jong-Woo Kim, Bo-Yeon Kim, Jin-Ho Shin, Woo Gyu Kim, Soo-Young Kim, Hyun-Jung Kim, Jeong-Soo Song, Jae-Bum Jun, Hyun-Ah Park, Shung Chull Chae, Bum Soon Choi, Tae Nyun Kim, Hyun Ah Kim
Korean J Intern Med. 2023;38(5):641-650. Published online August 28, 2023
Gout is the most common form of arthritis, with the prevalence increasing worldwide. The present treatment guidelines provide recommendations for the appropriate treatment of acute gout, management during the inter-critical period, and prevention of chronic complications. The guidelines were develop..
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| Original Articles |
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Gastroenterology
Efficacy and safety of 1 L polyethylene glycol plus ascorbic acid for bowel preparation in elderly: comparison with oral sulfate solution
Ki Young Lim, Kyeong Ok Kim, Eun Young Kim, Yoo Jin Lee, Byung Ik Jang, Sung Kook Kim, Chang Heon Yang; on behalf of Crohn’s and Colitis Association in Daegu-Gyeongbuk (CCAiD)
Korean J Intern Med. 2023;38(5):651-660. Published online July 24, 2023
Background/Aims: Recently, 1 L of polyethylene glycol (PEG) plus ascorbic acid (Asc) has been introduced in Korea as a colonoscopy preparation agent. Data on its efficacy and safety in older adults have been limited. We aimed to evaluate the safety and efficacy of 1 L PEG/Asc in older adults by comp..
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Real-world effectiveness and safety of adalimumab in Korean patients with intestinal Behcet’s disease: a Korean Association for the Study of Intestinal Diseases (KASID) multicenter study
Seung Bum Lee, Hee Seung Hong, Chang Kyun Lee, Bo-In Lee, Sol Kim, Seong-Joon Koh, Hosun Yu, Jung-Bin Park, Sung Wook Hwang, Byong Duk Ye, Suk-Kyun Yang, Sang Hyoung Park; on behalf of the IBD Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)
Korean J Intern Med. 2023;38(5):661-671. Published online July 26, 2023
Background/Aims: The short- and long-term effects of adalimumab (ADA) on Korean patients with intestinal Behcet’s disease (BD) for remain unclear. Therefore, a multicenter study was performed to evaluate the efficacy and safety of ADA in Korean patients with intestinal BD in a real-world setting.
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Diagnosis and management of acute colonic diverticulitis: results of a survey among Korean gastroenterologists
Jae Gon Lee, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Shin Hee Lee, Myung-Won You, Seong-Eun Kim
Korean J Intern Med. 2023;38(5):672-682. Published online August 17, 2023
Background/Aims: Some management strategies for acute colonic diverticulitis remain controversial in Korean real-world practice because their clinical features differ from those in the West. This study aimed to investigate the opinions of Korean physicians regarding the diagnosis and treatment of ac..
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Cardiology
Clinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice
Young Jin Youn, Jun-Won Lee, Sung Gyun Ahn, Seung-Hwan Lee, Junghan Yoon, Jae Hyoung Park, Sang-Yong Yoo, Woong Chol Kang, Nam Ho Lee, Ki Hwan Kwon, Joon Hyung Doh, Sang-Wook Lim, Yang Soo Jang, Dong Woon Jeon, Jung Ho Heo, Woong Gil Choi, Sungsoo Cho, Bong-Ki Lee, Hyonju Jeong, Bum-Kee Hong, Hyun-Hee Choi
Korean J Intern Med. 2023;38(5):683-691. Published online July 7, 2023
Background/Aims: The Genoss DES™ is a novel, biodegradable, polymer-coated, sirolimus-eluting stent with a cobalt- chromium stent platform and thin strut. Although the safety and effectiveness of this stent have been previously investigated, real-world clinical outcomes data are lacking. Therefore,..
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Clinical efficacy of angiotensin receptor-neprilysin inhibitor in de novo heart failure with reduced ejection fraction
Su Yeong Park, Min Gyu Kong, Inki Moon, Hyun Woo Park, Hyung-Oh Choi, Hye Sun Seo, Yoon Haeng Cho, Nae-Hee Lee, Kwan Yong Lee, Ho-Jun Jang, Je Sang Kim, Ik Jun Choi, Jon Suh
Korean J Intern Med. 2023;38(5):692-703. Published online August 31, 2023
Background/Aims: We aimed to analyze the efficacy of angiotensin receptor-neprilysin inhibitor (ARNI) by the disease course of heart failure (HF).
Methods: We evaluated 227 patients with HF in a multi-center retrospective cohort that included those with left ventricular ejection fraction (LVEF) ≤..
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Pulmonology
The impact of antimicrobial de-escalation therapy in culture-negative pneumonia: a systematic review and meta-analysis
Jae-Uk Song, Jonghoo Lee
Korean J Intern Med. 2023;38(5):704-713. Published online August 17, 2023
Background/Aims: Antimicrobial de-escalation (ADE) remains a challenging strategy in the treatment of pneumonia. We investigated the outcomes of ADE as measured by mortality and duration of the use of antibiotics in patients with culture- negative pneumonia.
Methods: We performed a systematic revie..
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The serotype-specific prevalence of pneumococci in hospitalized pneumonia patients with COPD: a prospective, multi-center, cohort study
Jae Yeol Kim, Jae-Woo Jung, Min-Jong Kang, Deog Kyeom Kim, Hayoung Choi, Young-Jae Cho, Seung Hun Jang, Chang-Hoon Lee, Yeon Mok Oh, Ji Sook Park
Korean J Intern Med. 2023;38(5):714-724. Published online August 17, 2023
Background/Aims: The overall incidence of pneumococcal pneumonia is declining. However, the change in the pathogenic distribution of community-acquired pneumonia (CAP) in chronic obstructive pulmonary disease (COPD) patients and the serotype specificity of Streptococcus pneumoniae have not be..
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Nephrology
Prognostic role of the neutrophil-to-lymphocyte ratio in patients with chronic kidney disease
Jin Kim, Su Hyun Song, Tae Ryom Oh, Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
Korean J Intern Med. 2023;38(5):725-733. Published online August 17, 2023
Background/Aims: The neutrophil-to-lymphocyte ratio (NLR) has a prognostic value in cardiovascular disease, infection, inflammatory disease, and several malignancies. Therefore, the NLR has a possible predictive value in patients with chronic kidney disease (CKD), but this predictive value has not b..
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Hemato-oncology
Rituximab plus multiagent chemotherapy for newly diagnosed CD20-positive acute lymphoblastic leukemia: a prospective phase II study
Dong Won Baek, Han-Seung Park, Sang Kyun Sohn, Dae Young Kim, Inho Kim, Jae-Sook Ahn, Young Rok Do, Se Ryeon Lee, Hyeon-Seok Eom, Won-Sik Lee, Sung-Hyun Kim, Ho Sup Lee, Yoo Jin Lee, Joon Ho Moon, Je-Hwan Lee; Adult Acute Lymphoblastic Leukemia Working Party, the Korean Society of Hematology
Korean J Intern Med. 2023;38(5):734-746. Published online June 20, 2023
Background/Aims: We performed a prospective study to determine the efficacy and safety of rituximab including chemotherapy in CD20-positive acute lymphoblastic leukemia (ALL).
Methods: Patients with newly diagnosed ALL, aged ≥ 15 years, were eligible for the study if their leukemic blast cells in ..
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Treatment pattern of chronic lymphocytic leukemia/small lymphocytic lymphoma in Korea: a multicenter retrospective study (KCSG LY20-06)
Jung Sun Kim, Tae Min Kim, Myoung Joo Kang, Sung Ae Koh, Hyunkyung Park, Seung-Hyun Nam, Jae Joon Han, Gyeong-Won Lee, Young Jin Yuh, Hee Jeong Lee, Jung Hye Choi
Korean J Intern Med. 2023;38(5):747-757. Published online June 26, 2023
Background/Aims: Little attention is paid to chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in Korea due to the rarity of the disease. With its rising incidence, we aimed to evaluate recent changes in treatment patterns and survival outcomes of patients with CLL/SLL.
Methods: A t..
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Infectious diseases
Antibiotics use patterns in end-of-life cancer patients and medical staff’s perception of antimicrobial stewardship programs
Min Kwan Kwon, Kyung Hwa Jung, Sungim Choi, Hyeonjeong Kim, Chang-Yun Woo, Mingee Lee, Jeong Geun Ji, Hyo-Ju Son
Korean J Intern Med. 2023;38(5):758-768. Published online August 17, 2023
Background/Aims: While most cancer patients with end-of-life (EOL) care receive antibiotic treatments, antibiotic use should be decided appropriately considering the benefits, side effects, resistance, and cost effects. Antimicrobial stewardship programs (ASP) are important for patients with EOL car..
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Rheumatology
Long-term renal outcomes of patients with non-proliferative lupus nephritis
Eun-Song Kang, Soo Min Ahn, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong
Korean J Intern Med. 2023;38(5):769-776. Published online August 7, 2023
Background/Aims: Although non-proliferative lupus nephritis (LN) (class I, II or V) has been considered as a less severe type of LN, data on long-term renal prognosis are limited. We investigated the long-term outcomes and prognostic factors in non-proliferative LN.
Methods: We retrospectively revi..
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| Images of interest |
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Uncovering the unforeseen: pericarditis and mycotic coronary aneurysm at previous stent site
Sook-Jung Kim, Osung Kwon, Jeong-Eun Yi, Joon-Kyu Kang, Yun-Seok Choi
Korean J Intern Med. 2023;38(5):779-780. Published online June 9, 2023
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An unusual cause of pneumonia: Strongyloides stercoralis infection
Chun-Jing Lu, Jin-Yan Zhang, Wei-Feng Huang
Korean J Intern Med. 2023;38(5):781-782. Published online June 20, 2023
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