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Rheumatology / Original Article
Increased risk of dementia in patients with primary Sjogren’s syndrome: a nationwide population-based cohort study
Kyung-Ann Lee, Hyeji Jeon, Hyun-Sook Kim, Kyomin Choi, Gi Hyeon Seo
Korean J Intern Med. 2025;40(2):330-338. Published online February 21, 2025
Background/Aims: This nationwide cohort study aimed to evaluate (1) whether primary Sjogren’s syndrome (pSS) can contribute to the development of dementia and (2) whether the use of hydroxychloroquine (HCQ) can decrease the incidence of dementia in patients with pSS using the Health Insurance Revi..
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Pulmonology / Review
Current perspectives on interstitial lung abnormalities
Ju Hyun Oh, Jin Woo Song
Korean J Intern Med. 2025;40(2):208-218. Published online March 1, 2025
Interstitial lung abnormalities (ILAs) are early indicators of interstitial lung disease, often identified incidentally via computed tomography of the chest. This review explores the diagnostic criteria for ILAs as outlined by the Fleischner Society, highlights associated risk factors, examines thei..
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Rheumatology / Original Article
Long-term outcome of interstitial lung disease in patients with primary Sjögren's syndrome: a retrospective observational study
Jung Hee Koh, Youngjae Park, Jennifer Lee, Howook Jeon, Su-Jin Moon, Yong Hyun Kim, Jun-Ki Min, Sung-Hwan Park, Seung-Ki Kwok
Korean J Intern Med. 2025;40(1):148-159. Published online October 25, 2024
Background/Aims: Interstitial lung disease (ILD) is a potentially serious but underdiagnosed manifestation of primary Sjögren's syndrome (pSS). This observational study investigated the prevalence and clinical course of ILD in pSS, together with prognostic factors.
Methods: A multicenter, retrosp..
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Rheumatology / Original Article
Effect of abatacept versus conventional synthetic disease modifying anti-rheumatic drugs on rheumatoid arthritis-associated interstitial lung disease
Kyung-Ann Lee, Bo Young Kim, Sung Soo Kim, Yun Hong Cheon, Sang-Il Lee, Sang-Hyon Kim, Jae Hyun Jung, Geun-Tae Kim, Jin-Wuk Hur, Myeung-Su Lee, Yun Sung Kim, Seung-Jae Hong, Suyeon Park, Hyun-Sook Kim
Korean J Intern Med. 2024;39(5):855-864. Published online August 30, 2024
Background/Aims: To compare the effects of abatacept and conventional synthetic disease modifying anti-rheumatic drugs (csDMARDs) on the progression and development of rheumatoid arthritis-associated interstitial lung disease (RA-ILD).
Methods: This multi-center retrospective study included RA pati..
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Rheumatology / Original Article
Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
Soo-Kyung Cho, Yeo-Jin Song, Jung-Yong Han, Hye Won Kim, Eunwoo Nam, Yoon-Kyoung Sung
Korean J Intern Med. 2024;39(4):680-690. Published online April 5, 2024
Background: To evaluate the effectiveness of Korean Red Ginseng (KRG) in managing fatigue in Korean patients with rheumatic diseases
Methods: Patients were randomly assigned to KRG (2 g/day, n = 60) or placebo (n = 60) groups for 12 weeks of blind phase and then open-label KRG from weeks 12 to 24 (..
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Hemato-oncology / Original Article
Prognostic Significance Of Sequential 18f-fdg Pet/Ct During Frontline Treatment Of Peripheral T Cell Lymphomas
Ga-Young Song, Sung-Hoon Jung, Seo-Yeon Ahn, Mihee Kim, Jae-Sook Ahn, Je-Jung Lee, Hyeoung-Joon Kim, Jang Bae Moon, Su Woong Yoo, Seong Young Kwon, Jung-Joon Min, Hee-Seung Bom, Sae-Ryung Kang, Deok-Hwan Yang
Korean J Intern Med. 2024;39(2):327-337. Published online January 25, 2024
Background/Aims: The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemo..
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Gastroenterology / Original Article
Radiology plus ileocolonoscopy versus radiology alone in Crohn’s disease: prognosis prediction and mutual agreement
Hye Kyung Hyun, Jongwook Yu, Eun Ae Kang, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Korean J Intern Med. 2022;37(3):567-578. Published online October 26, 2021
Background/Aims: The optimal tools for monitoring Crohn’s disease (CD) are controversial. We compared radiology plus ileocolonoscopy and radiology alone in terms of prognosis prediction and evaluated the agreement between radiologic and ileocolonoscopic findings in patients with CD.
Methods: Pati..
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Cardiology / Original Article
The current status and outcomes of in-hospital P2Y12 receptor inhibitor switching in Korean patients with acute myocardial infarction
Keun-Ho Park, Myung Ho Jeong, Hyun Kuk Kim, Young-Jae Ki, Sung Soo Kim, Youngkeun Ahn, Hyun Yi Kook, Hyo-Soo Kim, Hyeon Cheol Gwon, Ki Bae Seung, Seung Woon Rha, Shung Chull Chae, Chong Jin Kim, Kwang Soo Cha, Jong Seon Park, Jung Han Yoon, Jei Keon Chae, Seung Jae Joo, Dong-Joo Choi, Seung Ho Hur, In Whan Seong, Myeong Chan Cho, Doo Il Kim, Seok Kyu Oh, Tae Hoon Ahn, Jin Yong Hwang; on behalf of the KAMIR-NIH registry investigators
Korean J Intern Med. 2022;37(2):350-365. Published online January 12, 2022
Background/Aims: While switching strategies of P2Y12 receptor inhibitors (RIs) have sometimes been used in acute myocardial infarction (AMI) patients, the current status of in-hospital P2Y12RI switching remains unknown.
Methods: Overall, 8,476 AMI patients who underwent successful revascularization..
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Rheumatology / Original Article
Predictors of joint damage in patients with rheumatoid arthritis: focus on short- and long-term effects of intra-articular glucocorticoid injections
Jung Hee Koh, Hanna Lee, Seung-Geun Lee
Korean J Intern Med. 2021;36(6):1515-1526. Published online February 15, 2021
Background/Aims: To investigate the short- and long-term efficacy of intra-articular glucocorticoid injections (IAGI) in patients with rheumatoid arthritis (RA).
Methods: This was a retrospective study of RA patients who had active arthritis in the hand or wrist joints and who received IAGI (or not..
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Rheumatology / Original Article
Clinical influences of anticentromere antibody on primary Sjögren’s syndrome in a prospective Korean cohort
Youngjae Park, Jennifer Lee, Jung Hee Koh, Jung Yoon Choe, Yoon-Kyoung Sung, Shin-Seok Lee, Ji-Min Kim, Sung-Hwan Park, Seung-Ki Kwok
Korean J Intern Med. 2021;36(6):1492-1503. Published online August 24, 2020
Background/Aims: This study was performed to clarify inf luences of anticentromere antibody (ACA) on clinical phenotypes of primary Sjögren’s syndrome (pSS) patients in Korea. Methods: We assessed 318 patients who met the 2016 American College of Rheumatology/ European League Against Rheumatism cla..
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Review
Improving the care of inflammatory bowel disease (IBD) patients: perspectives and strategies for IBD center management
Jihye Park, Sinyoung Park, Shin Ae Lee, Soo Jung Park, Jae Hee Cheon
Korean J Intern Med. 2021;36(5):1040-1048. Published online August 5, 2021
The incidence and prevalence rates of inf lammatory bowel disease (IBD) have been increasing in East Asian countries over the past few decades. Accordingly, the general understanding and awareness of IBD among healthcare professionals has increased considerably in this region. This increase is ultim..
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Review
Clinical and genetic characteristics of Korean autosomal dominant polycystic kidney disease patients
Yun Kyu Oh, Hayne Cho Park, Hyunjin Ryu, Yong-Chul Kim, Kook-Hwan Oh
Korean J Intern Med. 2021;36(4):767-779. Published online July 1, 2021
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It is characterized by cyst growth in the kidneys, resulting in kidney enlargement and end-stage kidney disease. The polycystic kidney disease 1 (PKD1) and PKD2 have been identified as ge..
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Hemato-oncology / Original Article
Impact of subsequent chemotherapy on the survival of elderly patients with extensive stage small cell lung cancer
Eun Joo Kang, Yoon Ji Choi, Se Ryeon Lee, Hwa Jung Sung, Jung Sun Kim
Korean J Intern Med. 2020;35(6):1468-1476. Published online April 29, 2020
Background/Aims: The prognosis of small cell lung cancer (SCLC) is still poor because of rapid recurrence, despite good response to initial chemotherapy. Additionally, patients’ old ages and comorbidities are often obstacles that make it difficult to apply subsequent treatment after initial treatm..
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Review
Nutritional management in patients with chronic kidney disease
Sun Moon Kim, Ji Yong Jung
Korean J Intern Med. 2020;35(6):1279-1290. Published online September 23, 2020
The global prevalence of chronic kidney disease (CKD) is increasing with the aging of populations worldwide. As kidney function declines, the accumulation of metabolic waste products and excessive electrolytes can significantly impair the health of patients with CKD. As nutritional management of pat..
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Rheumatology / Original Article
Impact of sleep quality on clinical features of primary Sjögren's syndrome
Sang Wan Chung, Jaehyung Hur, You-Jung Ha, Eun Ha Kang, Joon Young Hyon, Hyo-Jung Lee, Yeong Wook Song, Yun Jong Lee
Korean J Intern Med. 2019;34(5):1154-1164. Published online February 20, 2018
Background/Aims: This study aimed to investigate the inf luence of poor sleep quality on clinical features of primary Sjögren’s syndrome (pSS).
Methods: Sleep quality was cross-sectionally assessed using the Pittsburgh Sleep Quality Index (PSQI), and demographic, clinical, and laboratory data we..
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Rheumatology / Original Article
Baseline extent of damage predicts spinal radiographic progression in Korean patients with ankylosing spondylitis treated with golimumab
Jeong Seok Lee, Yeong Wook Song, Tae Hwan Kim, Won Tae Chung, Seung Geun Lee, Sung Hwan Park, Gwan Gyu Song, Dae Young Yu, Stephen Xu, Eun Young Lee
Korean J Intern Med. 2018;33(3):622-628. Published online January 20, 2017
Background/Aims: For patients with ankylosing spondylitis (AS), golimumab has consistent efficacy in controlling disease activity over 5 years but its benefit in preventing radiographic progression was less clear at 4 years. To predict radiographic progression, we analyzed the baseline characteristi..
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Cardiology / Original Article
Anti-platelet effects of epigallocatechin-3-gallate in addition to the concomitant aspirin, clopidogrel or ticagrelor treatment
Hyung Joon Joo, Ji-Young Park, Soon Jun Hong, Kyoung-Ah Kim, Seung Hoon Lee, Jae-Young Cho, Jae Hyoung Park, Cheol Woong Yu, Do-Sun Lim
Korean J Intern Med. 2018;33(3):522-531. Published online October 19, 2017
Background/Aims: Although epigallocatechin-3-gallate (EGCG), which is found in high contents in the dried leaves of green tea, has been reported to have an anti-platelet effect, synergistic effects of EGCG in addition to current anti-platelet medications remains to be elucidated.
Methods: Blood sam..
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Cardiology / Review
Stent thrombosis and optimal duration of dual antiplatelet therapy after coronary stenting in contemporary practice
Min Soo Cho, Duk-Woo Park
Korean J Intern Med. 2017;32(5):769-779. Published online August 22, 2017
The introduction of drug-eluting stents (DES) in the practice of percutaneous coronary intervention (PCI) has substantially reduced angiographic and clinical restenosis but is associated with an increasing propensity for very late stent thrombosis (ST). Among several clinical, lesion, or procedure-r..
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Rheumatology / Original Article
Autonomic dysfunction in primary Sjogren’s syndrome: a prospective cohort analysis of 154 Korean patients
Jung Hee Koh, Seung-Ki Kwok, Jennifer Lee, Sung-Hwan Park
Korean J Intern Med. 2017;32(1):165-173. Published online March 25, 2016
Background/Aims: To determine the prevalence of autonomic dysfunction among Korean patients with primary Sjogren’s syndrome (pSS) and its associations with the clinical features of pSS. Methods: We analyzed 154 participants from the Korean Initiative of primary Sjogren’s Syndrome (KISS) as a pros..
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Letter to the editor
Successful treatment of sensorineural hearing loss in Sjögren’s syndrome with corticosteroid
Ki-Sik Kim, Hyun-Sook Kim
Korean J Intern Med. 2016;31(3):612-615. Published online April 8, 2016
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