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Cardiology / Original Article
Long-term clinical outcome and risk stratification across stages of cardiovascular-kidney-metabolic syndrome in a nationwide cohort
Hyun-Jin Kim, Byung Sik Kim, Hasung Kim, Jungkuk Lee, Ha Hye Jo, Dong Wook Kim, Jeong-Hun Shin, Ki-Chul Sung
Korean J Intern Med. 2025;40(6):975-989. Published online October 28, 2025
Background/Aims: Cardiovascular-kidney-metabolic (CKM) syndrome is a continuum of metabolic, cardiovascular, and kidney dysfunctions. This study aimed to evaluate the association between CKM stages and the risk of adverse composite clinical outcomes.
Methods: This retrospective cohort study used da..
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Review
Angiotensin-converting enzyme 2 and kidney diseases in the era of coronavirus disease 2019
Sang Heon Suh, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
Korean J Intern Med. 2021;36(2):247-262. Published online October 16, 2020
In the decades since the discovery of angiotensin-converting enzyme 2 (ACE2), its protective role in terms of antagonizing activation of the classical renin-angiotensin system (RAS) axis has been recognized in clinical and experimental studies on kidney and cardiovascular diseases. The effects of AC..
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Review
Optimal blood pressure target and measurement in patients with chronic kidney disease
Chang Seong Kim, Hong Sang Choi, Eun Hui Bae, Soo Wan Kim, Seong Kwon Ma
Korean J Intern Med. 2019;34(6):1181-1187. Published online June 17, 2019
The prevalence rates of hypertension and chronic kidney disease (CKD) are increasing with the aging of the population. Hypertension and CKD are closely related, and hypertension with accompanying CKD is difficult to control. This difficulty controlling blood pressure (BP) can be explained by changes..
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Nephrology / Original Article
Determinants and burden of chronic kidney disease in a high-risk population in Korea: results from a cross-sectional study
Yong Un Kang, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2016;31(5):920-929. Published online January 13, 2016
Background/Aims: This study aimed to investigate the prevalence of chronic kidney disease (CKD) and associated risk factors in a high-risk population in Korea.
Methods: A total of 6,045 participants aged ≥ 65 years (mean age, 73.0 ± 5.5) with diabetes or hypertension were enrolled. Participants w..
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Review
Autosomal Dominant Polycystic Kidney Disease: 2009 Update for Internists
William M. Bennett
Korean J Intern Med. 2009;24(3):165-168. Published online August 26, 2009
Because autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic abnormalities seen in today's medical practice, many internists will likely treat patients affected by this condition. Genetic abnormalities have been increasingly recognized, and the pathophysiology of..
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