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Original Article
Cost Analysis of Iron-Related Complications in a Single Institute
Ki Hwan Kim, Jin Won Kim, Ji young Rhee, Min-Kyung Kim, Byung-Su Kim, Inho Kim, Soo-Mee Bang, Sung-Soo Yoon, Jong-Seok Lee, Kyou-Sup Han, Seonyang Park, Byoung Kook Kim
Korean J Intern Med. 2009;24(1):33-36. Published online March 6, 2009
Background/AimsThe financial burden of caring for iron-related complications (IRCs) is an emerging medical problem in Korea, as in Western countries. We produced a preliminary estimate of the costs of treating patients for IRCs. Methods<..
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Original Article
Relationship Between Left Atrial Size and Stroke in Patients With Sinus Rhythm and Preserved Systolic Function
Bong Soo Kim, Hyun Jik Lee, Jae Hoon Kim, Hee Sang Jang, Byung Seok Bae, Hyun Jae Kang, Bong Ryeol Lee, Byung Chun Jung
Korean J Intern Med. 2009;24(1):24-32. Published online March 6, 2009
Background/AimsIncreased left atrial (LA) size has been proposed as a predictor of poor cardiovascular outcome in the elderly. In the present study, we evaluated the relationship between LA size and stroke in subjects of all ages who presented with preserved left ventricular s..
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Original Article
Reproducibility of Regional Pulse Wave Velocity in Healthy Subjects
Nak Bum Lee, Chang Gyu Park
Korean J Intern Med. 2009;24(1):19-23. Published online March 6, 2009
Background/AimsDespite the clinical importance and widespread use of pulse wave velocity (PWV), there are no standards for pulse sensors or for system requirements to ensure accurate pulse wave measurement. We assessed the reproducibility of PWV values using a newly developed ..
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Original Article
Clinical Features and Prognostic Factors of Anaerobic Infections: A 7-Year Retrospective Study
Yoonseon Park, Jun Young Choi, Dongeun Yong, Kyungwon Lee, June Myung Kim
Korean J Intern Med. 2009;24(1):13-18. Published online March 6, 2009
Background/AimsRisk factors for mortality resulting from anaerobic infection are incompletely defined. The clinical significance of a broad range of pathogenic obligate anaerobic organisms was examined, and factors independently associated with mortality were identified in pat..
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Review
Overview of Therapeutic Drug Monitoring
Ju-Seop Kang, Min-Ho Lee
Korean J Intern Med. 2009;24(1):1-10. Published online March 6, 2009
Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens. It is unnecessary to employ TDM for the majority of medications, and it is..
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Case Report
A case of granulomatous lung disease in a patient with Good's syndrome
Seung Heon Lee, Sang-Min Lee, Seok-Chul Yang, Chul-Gyu Yoo, Young Whan Kim, Young-Soo Shim, Sung Koo Han
Korean J Intern Med. 2008;23(4):219-222. Published online December 30, 2008
Good's syndrome is extremely rare. This adult-onset condition is characterized by a thymoma with immunodeficiency, low B- and T-cell counts, and hypo-gammaglobulinemia. The initial clinical presentation is either a mass-lesion thymoma or a recurrent infection. Patients with Good's syndrome are ve..
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Case Report
A case of congenital bilateral coronary-to-right ventricle fistula coexisting with variant angina
Se-Na Jang, Sung-Ho Her, Kyong-Rock Do, Joon-Sung Kim, Hee-Jeong Yoon, Jong-Min Lee, Seung-Won Jin
Korean J Intern Med. 2008;23(4):216-218. Published online December 30, 2008
A coronary arteriovenous (AV) fistula consists of a communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common anomaly that can affect coronary perfusion. Yet bilateral involvement of a coronary fistula, constitutes an uncommon subgroup o..
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Case Report
A case of scar sarcoidosis
Young Chul Hong, Dong Jib Na, Sang Hoon Han, Yang Deok Lee, Yong Seon Cho, Min Soo Han
Korean J Intern Med. 2008;23(4):213-215. Published online December 30, 2008
Infiltration of sarcoid granuloma in old cutaneous scars is one of the uncommon cutaneous manifestations of sarcoidosis. Here, we report the case of a 47-year-old female who presented with swelling and irritation in 5 old scars. She had acquired these scars 9 years ago in a traffic accident. An i..
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Case Report
A case of blue rubber bleb nevus syndrome
Seung-Hwan Shin, Hiun-Suk Chae, Jeong-Seon Ji, Hyung-Keun Kim, Young-Seok Cho, Eun-Deok Chang, Kyu-Yong Choi
Korean J Intern Med. 2008;23(4):208-212. Published online December 30, 2008
Blue rubber bleb nevus syndrome is a rare disorder that is characterized by multiple recurrent vascular malformations, such as hemangioma, and these primarily involve the skin and the gastrointestinal tract. It may also involve the brain, liver, lungs, and skeletal muscles. A 14-year-old female v..
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Original Article
Polymorphism in the promoter region of the klotho gene (G-395A) is associated with early dysfunction in vascular access in hemodialysis patients
Youngsu Kim, Sun Joo Jeong, Hyung Suk Lee, Eun Jung Kim, Young Rim Song, Sung Gyun Kim, Ji Eun Oh, Young Ki Lee, Jang Won Seo, Jong Woo Yoon, Ja-Ryong Koo, Hyung Jik Kim, Jung Woo Noh, Seung Ho Park
Korean J Intern Med. 2008;23(4):201-207. Published online December 30, 2008
Background/AimsVascular access dysfunction is an important cause of morbidity and mortality in hemodialysis (HD) patients. Recent studies have shown that a klotho gene mutation is related to endothelial dysfunction, thrombosis, and arteriosclerosis, which are ..
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Original Article
Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease
Jae Won Yang, Min Soo Kim, Jae Seok Kim, Jong Myoung Yoo, Seung Tae Han, Bi Ro Kim, Yun Deok Kim, Jeong Wook Choi, Seung Ok Choi, Byoung Geun Han
Korean J Intern Med. 2008;23(4):191-200. Published online December 30, 2008
Background/AimsBrain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients ..
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Original Article
Autologous stem cell transplantation for diffuse large B-cell lymphoma with residual extranodal involvement
Ock Bae Ko, Geundoo Jang, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2008;23(4):182-190. Published online December 29, 2008
Background/AimsDiffuse large B-cell lymphoma (DLBCL) in Koreans is frequently accompanied by extranodal (EN) disease at the time of autologous stem cell transplantation (ASCT). We sought to determine whether high EN involvement affected survival following ASCT in Koreans. <..
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Original Article
Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics
Inseon S. Choi, Yong Cui, Young-Ah Koh, Hyun-Chul Lee, Yong-Bum Cho, Young-Ho Won
Korean J Intern Med. 2008;23(4):176-181. Published online December 30, 2008
Background/AimsThe androgen dehydroepiandrosterone (DHEA) attenuates allergic inflammatory airway reactions by down-regulating the Th2 response in mice. The purpose of this study was to investigate whether DHEA suppresses Th2 cytokine production in cultured peripheral blood m..
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Original Article
Factors for poor prognosis of near-fatal asthma after recovery from a life-threatening asthma attack
Myung-Shin Kim, Young-Joo Cho, Hee-Bom Moon, Sang Heon Cho
Korean J Intern Med. 2008;23(4):170-175. Published online December 29, 2008
Background/AimsThe aim of this study was to investigate poor prognostic factors associated with a near-fatal asthma attack following patient recovery. MethodsWe enrolled 68 patients who suffered near-fatal asthma attacks and w..
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Original Article
Hepatocyte nuclear factor 1-alpha mutation in normal glucose-tolerant subjects and early-onset type 2 diabetic patients
Dong Mee Lim, Nam Huh, Keun Yong Park
Korean J Intern Med. 2008;23(4):165-169. Published online December 29, 2008
Background/AimsThe prevalence of diabetes in Korea is reported to be approximately 10%, but cases of maturity-onset diabetes of the young (MODY) are rare in Korea. A diagnostic technique for autosomal dominant MODY is being actively sought. In this regard, we used a DNA chip t..
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Case Report
High-dose Immunoglobulin Infusion for Thrombotic Thrombocytopenic Purpura Refractory to Plasma Exchange and Steroid Therapy
Seh Jong Park, Seok Jin Kim, Hee Yun Seo, Moon Ju Jang, Doyeun Oh, Byung Soo Kim, Jun Suk Kim
Korean J Intern Med. 2008;23(3):161-164. Published online September 20, 2008
The outcomes of the treatment of thrombotic thrombocytopenic purpura (TTP) have been shown to be improved by the administration of plasma exchange. However, treatment options are currently limited for cases refractory to plasma exchange. The autoantibodies that block the activity of ADAMTS13 have..
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Case Report
Hemorrhagic pericarditis with cardiac tamponade after percutaneous coronary intervention associated with the use of abciximab
Su-Jin Moon, Hee-Jeoung Yoon, Sung-Ho Her, Jong-Min Lee, Ho-Jung An, Yune-Jeong Lee, Seung-Won Jin
Korean J Intern Med. 2008;23(3):156-160. Published online September 20, 2008
Glycoprotein (GP) IIb/IIIa inhibitors, such as abciximab, are used as adjunctive therapy for percutaneous coronary intervention (PCI) in high-risk non-ST-elevation myocardial infarction (NSTEMI) and in ST-elevation myocardial infarction (STEMI), although their effects when used for STEMI are less..
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Case Report
Spontaneous rupture of the lateral thoracic artery in patients with liver cirrhosis
Tae Hee Lee, Yong Sung Park, Dong Jin Chung, Ji Hyung Kim, Sun Moon Kim, Euyi Hyeog Im, Kyu Chan Huh
Korean J Intern Med. 2008;23(3):152-155. Published online September 20, 2008
Bleeding in patients with liver cirrhosis is primarily caused by gastroesophageal varix in association with extensive collateral circulation, portal hypertensive gastropathy, a Mallory-Weiss tear and peptic ulcer disease. The spontaneous rupture of an artery, as a result of coagulopathy, is extre..
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Case Report
Lupus anticoagulant-hypoprothrombinemia in healthy adult
Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2008;23(3):149-151. Published online September 20, 2008
The presence of lupus anticoagulant is associated with an elevated risk of venous and arterial thrombosis, and recurrent miscarriages as well. For some cases, this disease can present with bleeding as a consequence of lupus anticoagulant hypoprothrombinemia (LAHPS). LAHPS is a rare disease and it..
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Original Article
Recent clinical overview of renal and perirenal abscesses in 56 consecutive cases
Bong Eun Lee, Hee Yun Seol, Tae Kyung Kim, Eun Young Seong, Sang Heon Song, Dong Won Lee, Soo Bong Lee, Ihm Soo Kwak
Korean J Intern Med. 2008;23(3):140-148. Published online September 20, 2008
Background/AimsThe aim of this study was to examine the recent clinical trends and antibiotic susceptibilities of the causative microorganisms in renal and perirenal abscesses, and to elucidate the factors associated with treatment strategies. ..
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