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Original Article
Thalidomide for Treating Metastatic Hepatocellular Carcinoma: A Pilot Study
Sang Hoon Han, Se Hoon Park, Jung Ho Kim, Jong Jun Lee, So Young Kwon, Oh Sang Kwon, Sun Suk Kim, Ju Hyun Kim, Keon Kug Kim, Yeon Ho Park, Jeong Nam Lee, Eunmi Nam, Soo-Mee Bang, Eun Kyung Cho, Dong Bok Shin, Jae Hoon Lee
Korean J Intern Med. 2006;21(4):225-229. Published online December 31, 2006
BackgroundThalidomide has been reported to have antitumor activity for treating metastatic hepatocellular carcinoma (HCC). We evaluated the safety and efficacy of using thalidomide for treating selected patients with unresectable or metastatic HCC, and their disease was refrac..
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Original Article
Diagnostic Usefulness of the Janus Kinase 2 Mutation in non BCR/ABL Myeloproliferative Disorders
Soo-Mee Bang, Jeong Yeal Ahn, Jiyoon Park, Soo Jin Yoo, Se Hoon Park, Eun Mi Nam, Pil Whan Park, Yiel Hea Seo, Eun Kyung Cho, Dong Bok Shin, Jae Hoon Lee
Korean J Intern Med. 2006;21(4):219-224. Published online December 31, 2006
BackgroundWe investigated the Janus kinase 2 (JAK2) mutation and its diagnostic value in patients suffering with non BCR/ABL myeloproliferative diseases (nMPD) or other reactive conditions. Methods..
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Case Report
Tachycardiomyopathy Induced by Ventricular Premature Complexes: Complete Recovery after Radiofrequency Catheter Ablation
Kyoung-Hoon Rhee, Ju-Young Jung, Kyoung-Suk Rhee, Hyun-Sook Kim, Jei-Keon Chae, Won-Ho Kim, Jae-Ki Ko
Korean J Intern Med. 2006;21(3):213-217. Published online September 30, 2006
Ventricular premature complexes (VPCs) are known to be one of the most benign cardiac arrhythmias when they occur in structurally normal hearts. We experienced a 32-year old man who presented with dyspnea, palpitations and very frequent VPCs (31% of the total heart beats). Echocardiography reveal..
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Case Report
A Case of Multiple Organ Failure due to Heat Stoke Following a Warm Bath
Seung Young Kim, Su Ah Sung, Gang Jee Ko, Chang Su Boo, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim
Korean J Intern Med. 2006;21(3):210-212. Published online September 30, 2006
Heat stroke is a potentially fatal disorder that's caused by an extreme elevation in body temperature. We report here an unusual case of multiple organ failure that was caused by classical, nonexertional heat stroke due to taking a warm bath at home. A 68 year old diabetic man was hospitalized fo..
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Case Report
Hepatic Subcapsular Steatosis in a Diabetic CAPD Patient Receiving Intraperitoneal Insulin
Eun Chul Jang, Guilsun Kim, Young Soo Kim, Sun Ae Yoon, Young Mi Ku, Chul Woo Yang, Young Ok Kim
Korean J Intern Med. 2006;21(3):206-209. Published online September 30, 2006
Hepatic subcapsular steatosis is a rare and specific form of fatty change in the liver. It is a unique finding in diabetic patients receiving continuous ambulatory peritoneal dialysis (CAPD) and intraperitoneal insulin treatment. Intraperitoneal administration of insulin causes a unique pattern o..
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Case Report
A Case of Nonsecretory Multiple Myeloma with Atypical Imaging Features
Hwa Yeon Lee, Seung Min Yoo, In Sup Song, Hyeon Yu, Jong Beum Lee, Jong Wook Shin, In Won Park
Korean J Intern Med. 2006;21(3):202-205. Published online September 30, 2006
Multiple myeloma usually shows homogeneous enhancement on contrast-enhanced Magnetic Resonance imaging (MRI), and is accompanied by a monoclonal gammopathy in serum or urine. We report a case of nonsecretory myeloma, the diagnosis was difficult due to the absence of a monoclonal gammopathy and th..
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Case Report
A Case of Benign Metastasizing Leiomyoma with Multiple Metastasis to the Soft Tissue, Skeletal Muscle, Lung and Breast
Ji Hoon Jo, Jin Hwa Lee, Dae Cheol Kim, Sung Hyun Kim, Hyuk Chan Kwon, Jae Seok Kim, Hyo Jin Kim
Korean J Intern Med. 2006;21(3):199-201. Published online September 30, 2006
Benign metastasizing leiomyoma (BML) is composed of well-differentiated smooth muscle cells and dense connective tissue. BML affects middle-aged women who have had previous hysterectomies due to a histologically benign-appearing uterine leiomyoma. We report here on a case of BML from the uterine ..
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Case Report
High-grade Hepatic Mucosa-associated Lymphoid Tissue (MALT) Lymphoma Probably Transformed from the Low-grade Gastric MALT Lymphoma
Yong Woo Chung, Joo Hyun Sohn, Chang Hee Paik, Jae Yoon Jeong, Dong Soo Han, Yong Cheol Jeon, Young Ha Oh
Korean J Intern Med. 2006;21(3):194-198. Published online September 30, 2006
The Mucosa-associated lymphoid tissue (MALT) lymphoma, which was first described in 1983, is known to be caused by chronic Helicobacter pylori (HP) infection, which triggers lymphoid infiltration and formation of organized lymphoid tissue. In approximately two thirds of cases of ..
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Case Report
Small Cell Carcinoma of the Kidney
Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2006;21(3):191-193. Published online September 30, 2006
Up to 5% of all small cell carcinomas develop at extrapulmonary sites. Primary small cell carcinomas originating in the kidney are extremely rare neoplasms. Here we report a case of primary small cell carcinoma of the kidney. A nephrectomy was performed on a 52-year-old female patient to remove a..
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Case Report
Transluminal Removal of a Fractured and Embolized Indwelling Central Venous Catheter in the Pulmonary Artery
O Kil Kim, Su Hong Kim, Jong Bin Kim, Woo Seong Jeon, Sung Hwan Jo, Jee Hyun Lee, Ji Ho Ko
Korean J Intern Med. 2006;21(3):187-190. Published online September 30, 2006
Vascular catheters are associated with complications such as infection, thrombosis and stenosis. The embolization of a venous catheter fragment is a rare complication. A 39-year-old woman underwent placement of a totally implantable venous access device for chemotherapy to treat a recurrent lipos..
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Case Report
Two Cases of Interstitial Pneumonitis Caused by Rituximab Therapy
Yuna Lee, Sun Young Kyung, Soo Jin Choi, Soo-Mee Bang, Seong Hwan Jeong, Dong Bok Shin, Jae Hoon Lee
Korean J Intern Med. 2006;21(3):183-186. Published online September 30, 2006
Rituximab, a chimeric monoclonal antibody directed against CD20, has become a part of the standard therapy for patients with non-Hodgkin's lymphoma either in combination with other drugs or as a single agent. The CD20 antigen is expressed on 95% of B-cell lymphoma cells and normal B-cells but, is..
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Case Report
Photodynamic Therapy in Early Lung Cancer: A Report of Two Cases
Tae Won Jang, Hee Kyoo Kim, Chul Ho Oak, Mann Hong Jung
Korean J Intern Med. 2006;21(3):178-182. Published online September 30, 2006
Photodynamic therapy (PDT) that is based on the science of photochemistry has been recognized as a lung sparing local therapeutic modality that can achieve remarkable responses. It is an alternative treatment for early stage lung cancer patients who have poor lung function or multiple sites of ca..
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Case Report
Benign Pulmonary Metastasizing Leiomyomatosis: Case Report and a Review of the Literature
Young-Il Kwon, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Dong Ho Shin, Sung Soo Park
Korean J Intern Med. 2006;21(3):173-177. Published online September 30, 2006
The authors report here on a case of a nearly asymptomatic 51-year-old Korean woman who was found to have diffuse, multiple nodules of the lungs on a routine chest radiograph. She had undergone hysterectomy 16 years previously for uterine myoma. An open lung biopsy revealed tumor that was compose..
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Original Article
Intravenous Itraconazole vs. Amphotericin B Deoxycholate for Empirical Antifungal Therapy in Patients with Persistent Neutropenic Fever
Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Woo-Sung Min, Wan-Shik Shin
Korean J Intern Med. 2006;21(3):165-172. Published online September 30, 2006
BackgroundAmphotericin B dexoycholate is currently the standard empirical antifungal therapy for neutropenic patients with hematologic malignancies and who also have persistent fever that does not respond to antibacterial therapy. The antifungal triazoles offer a potentially s..
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Original Article
ESHAP Salvage Therapy for Refractory and Relapsed Non-Hodgkin's Lymphoma: A Single Center Experience
Sang Hyoung Park, Shin Kim, Ok Bae Ko, Ja Eun Koo, Danbi Lee, Yong Pil Jeong, Jooryung Huh, Sung-Bae Kim, Sang We Kim, Jae-Lyun Lee, Cheolwon Suh
Korean J Intern Med. 2006;21(3):159-164. Published online September 30, 2006
BackgroundThe ESHAP chemotherapy regimen, that is, the combination of the etoposide, methylprednisolone, high-dose cytarabine and cisplatin, has been shown to be active against relapsing or refractory non-Hodgkin's lymphoma (NHL) in previous therapeutic trials. We attempted to..
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Case Report
Hemorrhagic Fever with Renal Syndrome Complicated with Pregnancy: A Case Report
Baek-Nam Kim, Byung-Don Choi
Korean J Intern Med. 2006;21(2):150-153. Published online June 30, 2006
Hantaviruses cause two forms of human disease: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome. Hantavirus infection can occur in pregnant women and it can have an influence on the maternal and fetal outcomes, although this is a rare finding even in endemic areas. W..
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Case Report
Coronary Artery Intervention after Cytostatics Treatment in Unstable Angina Patient with Essential Thrombocythemia. A Case Report and Literature Review
Hyun Chang, Chi Young Shim, June-Won Cheong, Ju-Yeon Pyo, Young Guk Ko, Donghoon Choi, Yangsoo Jang
Korean J Intern Med. 2006;21(2):146-149. Published online June 30, 2006
Essential thrombocythemia (ET) is a clonal disorder of myeloid stem cells that causes thrombocytosis. As a result, ET can lead to vascular thrombosis and tissue ischemia; the association of coronary artery abnormalities such as myocardial infarction or unstable angina is rare. Here we describe a ..
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Case Report
A Case of a Composite Adrenal Medullary Tumor of Pheochromocytoma and Ganglioneuroma Masquerading as Acute Pancreatitis
Eun-Kyoung Choi, Wan-Ho Kim, Keun-Yong Park
Korean J Intern Med. 2006;21(2):141-145. Published online June 30, 2006
Composite adrenal medullary tumors, composed of both pheochromocytoma and ganglioneuroma, are extremely rare, as are pheochromocytomas masquerading as acute relapsing pancreatitis. We recently experienced a case of a 48-year-old male with both these phenomena. The patient complained of an acute o..
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Case Report
A Case of Acute Eosinophilic Myopericarditis Presenting with Cardiogenic Shock and Normal Peripheral Eosinophil Count
Il Suk Sohn, Jong Chun Park, Jae Hun Chung, Kye Hun Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho
Korean J Intern Med. 2006;21(2):136-140. Published online June 30, 2006
Eosinophilic myocarditis usually results from myocardial damage as a result of drugs or parasites, and is generally associated with increased peripheral eosinophil count. This form of myocarditis is difficult to diagnose clinically. A 25 year-old previously healthy woman was transferred fro..
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