Gastroenterology / Original Article Increasing correlation between oral and gastric microbiota during gastric carcinogenesis Hee Sang You, Jae Yong Park, Hochan Seo, Beom Jin Kim, Jae Gyu Kim Korean J Intern Med. 2024;39(4):590-602.   Published online June 24, 2024 DOI: https://doi.org/10.3904/kjim.2023.490              Web of Science 1    Crossref 2                      Background/Aims: Recent research has increasingly focused on the role of the gastric microbiome in the development of gastric cancer. We aimed to investigate the changes in the microbiome during gastric carcinogenesis in structural and functional aspects, with a specific focus on the association bet..

Gastroenterology / Original Article Efficacy comparison of high-genetic barrier nucleos(t)ide analogues in treatment-naïve chronic hepatitis B patients: a network meta-analysis Jaejun Lee, Ahlim Lee, Pil Soo Sung, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Hyun Yang Korean J Intern Med. 2024;39(4):577-589.   Published online June 13, 2024 DOI: https://doi.org/10.3904/kjim.2023.311                      Background/Aims: Four high-genetic barrier nucleos(t)ide analogues (NAs) for chronic hepatitis B (CHB), namely entecavir (ETV), tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), and besifovir dipivoxil maleate (BSV), have been established. The aim of this study is to investigate the ..

Gastroenterology / Review Approaches and considerations in the endoscopic treatment of T1 colorectal cancer Yunho Jung Korean J Intern Med. 2024;39(4):563-576.   Published online May 14, 2024 DOI: https://doi.org/10.3904/kjim.2023.487                 The detection of early colorectal cancer (CRC) is increasing through the implementation of screening programs. This increased detection enhances the likelihood of minimally invasive surgery and significantly lowers the risk of recurrence, thereby improving patient survival and reducing mortality rat..

Gastroenterology / Review Artificial intelligence in colonoscopy: from detection to diagnosis Eun Sun Kim, Kwang-Sig Lee Korean J Intern Med. 2024;39(4):555-562.   Published online May 2, 2024 DOI: https://doi.org/10.3904/kjim.2023.332                 This study reviews the recent progress of artificial intelligence for colonoscopy from detection to diagnosis. The source of data was 27 original studies in PubMed. The search terms were “colonoscopy” (title) and “deep learning” (abstract). The eligibility criteria were: (1) the dependent varia..

Gastroenterology / Review Strategies to improve screening colonoscopy quality for the prevention of colorectal cancer Joo Hye Song, Eun Ran Kim Korean J Intern Med. 2024;39(4):547-554.   Published online January 22, 2024 DOI: https://doi.org/10.3904/kjim.2023.334              Web of Science 2    Crossref 2                 The incidence and mortality of colorectal cancer (CRC) have decreased through regular screening colonoscopy, surveillance, and endoscopic treatment. However, CRC can still be diagnosed after negative colonoscopy. Such CRC is called interval CRC and accounts for 1.8–9.0% of all CRC cases. Most case..

Gastroenterology / Image of interest An unusual cause of a huge abscess in the thigh Dae Gon Ryu, Su Bum Park, Cheol Woong Choi, Su Jin Kim, Hyeong Seok Nam Korean J Intern Med. 2024;39(3):537-538.   Published online November 30, 2023 DOI: https://doi.org/10.3904/kjim.2023.305

Gastroenterology / Original Article Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis Aryoung Kim, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Myung Ji Goh Korean J Intern Med. 2024;39(3):448-457.   Published online April 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.354              Web of Science 2    Crossref 2                      Background/Aims: Improved knowledge of local epidemiology and predicting risk factors of multidrug-resistant (MDR) bacteria are required to optimize the management of infections. This study examined local epidemiology and antibiotic resistance patterns of liver cirrhosis (LC) patients and evaluated ..

Gastroenterology / Original Article Predicting Helicobacter pylori infection from endoscopic features Jun-young Seo, Ji Yong Ahn, Seonok Kim, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung Korean J Intern Med. 2024;39(3):439-447.   Published online April 30, 2024 DOI: https://doi.org/10.3904/kjim.2023.300              Web of Science 1    Crossref 2                      Background: Helicobacter pylori infection, prevalent in more than half of the global population, is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. The effectiveness of early diagnosis and treatment in preventing gastric cancer highlights the nee..

Gastroenterology / Original Article Self-screening questionnaire for perianal fistulizing disease in patients with Crohn’s disease O Seong Kweon, Ben Kang, Yoo Jin Lee, Eun Soo Kim, Sung Kook Kim, Hyun Seok Lee, Yun Jin Chung, Kyeong Ok Kim, Byung Ik Jang; on behalf of Crohn’s Colitis Association in Daegu-Gyeongbuk (CCAiD) Korean J Intern Med. 2024;39(3):430-438.   Published online April 5, 2024 DOI: https://doi.org/10.3904/kjim.2023.410                 Background/Aims: A poor prognostic factor for Crohn’s disease (CD) includes perianal fistulizing disease, including perianal fistula and/or perianal abscess. Currently, a tool to assess perianal symptoms in patients with CD remains nonexistent. This study aimed to develop a perianal fistulizing di..

Gastroenterology / Editorial Decompensated cirrhosis and antibiotic prophylaxis: striking a delicate balance Jung Gil Park Korean J Intern Med. 2024;39(3):369-370.   Published online April 30, 2024 DOI: https://doi.org/10.3904/kjim.2024.119

Gastroenterology / Original Article Reduced risk of gastrointestinal bleeding associated with eupatilin in aspirin plus acid suppressant users: nationwide population-based study Hyun Seok Lee, Ji Hyung Nam, Dong Jun Oh, Yeo Rae Moon, Yun Jeong Lim Korean J Intern Med. 2024;39(2):261-271.   Published online December 14, 2023 DOI: https://doi.org/10.3904/kjim.2023.324              Web of Science 2    Crossref 2                 Background/Aims: Mucoprotective agents, such as eupatilin, are often prescribed to prevent gastrointestinal (GI) bleeding in addition to an acid suppressant despite the absence of a large-scale study. We evaluated the additional effect of eupatilin on the prevention of GI bleeding in both the upper ..

Gastroenterology / Original Article Model for end-stage liver disease-3.0 vs. model for end-stage liver disease-sodium: mortality prediction in Korea Jeong Han Kim, Yong Joon Cho, Won Hyeok Choe, So Young Kwon, Byung-Chul Yoo Korean J Intern Med. 2024;39(2):248-260.   Published online February 1, 2024 DOI: https://doi.org/10.3904/kjim.2023.005              Web of Science 6    Crossref 3                 Background/Aims: The model for end-stage liver disease (MELD) serves as an indicator for short-term mortality among patients diagnosed with liver cirrhosis (LC) and is used to prioritize patients for liver transplantation. In 2021, the updated version of MELD, MELD-3.0, was introduced to improve the..

Gastroenterology / Original Article Endoscopic mucosal resection using anchored snare Tip-in versus precut technique for small rectal neuroendocrine tumors Seung Wook Hong, Dong-Hoon Yang, Yoo Jin Lee, Dong Hoon Baek, Jaeyoung Chun, Hyun Gun Kim, Sung Joo Kim, Seung-Mo Hong, Dae-Seong Myung Korean J Intern Med. 2024;39(2):238-247.   Published online December 8, 2023 DOI: https://doi.org/10.3904/kjim.2023.263                      Background/Aims: Small rectal neuroendocrine tumors (NETs) can be treated with modified endoscopic mucosal resection (EMR). However, an optimal EMR method remains to be established. We aimed to assess the non-inferiority of Tip-in EMR versus precut EMR (EMR-P) for treating rectal NETs. Methods: Thi..

Gastroenterology / Original Article The combined use of anti-peptic agents is associated with an increased risk of osteoporotic fracture: a nationwide case-control study Dong Jun Oh, Ji Hyung Nam, Hyun Seok Lee, Yeo Rae Moon, Yun Jeong Lim Korean J Intern Med. 2024;39(2):228-237.   Published online February 7, 2024 DOI: https://doi.org/10.3904/kjim.2023.326              Web of Science 1    Crossref 1                 Background/Aims: Long-term use of acid suppressants such as proton pump inhibitors (PPIs) and histamine 2 receptor antagonist (H2RA) has been associated with the risk of osteoporotic fracture. Acid suppressants and muco-protective agents (MPAs) are often used together as anti-ulcer agents. We evalua..

Gastroenterology / Editorial Navigating the risks of using concomitant antipeptic agents in light of osteoporotic concerns Hae Won Yoo, Su Jin Hong Korean J Intern Med. 2024;39(2):201-202.   Published online February 28, 2024 DOI: https://doi.org/10.3904/kjim.2024.048

Gastroenterology / Original Article Usefulness of nasal cavity evaluation before high-resolution esophageal manometry in high-risk patients Hyun Jin Min, Jae Yong Park Korean J Intern Med. 2024;39(1):86-94.   Published online November 30, 2023 DOI: https://doi.org/10.3904/kjim.2023.266                      Background/Aims: A catheter is inserted through the nasal cavity during high-resolution esophageal manometry (HRM), which may cause adverse events such as pain or epistaxis. Despite these possible safety considerations, studies on this subject are very limited. We aimed to investigate the usefulness..

Gastroenterology / Original Article Risk factors for anticoagulant-associated gastrointestinal hemorrhage: a systematic review and meta-analysis Fuxin Ma, Shuyi Wu, Shiqi Li, Zhiwei Zeng, Jinhua Zhang Korean J Intern Med. 2024;39(1):77-85.   Published online December 8, 2023 DOI: https://doi.org/10.3904/kjim.2023.098                      Background/Aims: There may be many predictors of anticoagulation-related gastrointestinal bleeding (GIB), but until now, systematic reviews and assessments of the certainty of the evidence have not been published. We conducted a systematic review to identify all risk factors for anticoagulant-associ..

Gastroenterology / Original Article Histologic features and predicting prognosis in ulcerative colitis patients with mild endoscopic activity Seung Yong Shin, Hee Sung Kim, Kisung Kim, Chang Won Choi, Jung Min Moon, Jeong Wook Kim, Hyun Jin Joo, Jeongkuk Seo, Muhyeon Sung, Chang Hwan Choi Korean J Intern Med. 2024;39(1):68-76.   Published online December 13, 2023 DOI: https://doi.org/10.3904/kjim.2023.167              Web of Science 2    Crossref 2                      Background/Aims: We aimed to evaluate the histologic features predictive of prognosis and correlate them with endoscopic findings in patients with ulcerative colitis (UC) having complete or partial mucosal healing (MH). Methods: We prospectively collected and reviewed data from patients with UC who..

Gastroenterology / Original Article Comparative study of the efficacy and safety of Abexol (suspension versus tablets) in patients with gastrointestinal symptoms Alfredo Hierro González, Julio César Fernández Travieso, Yoandy Hernández Casas, Susana Borges González, María de los Angeles Camacho Morales, Elena Ferrer Batallie, Anaisa Roja Carralera, Yenney Reyes Nuñez, Sarahi Mendoza Castaño, Maytee Robaina García, Diana Margarita Rey Kaba Korean J Intern Med. 2024;39(1):57-67.   Published online November 30, 2023 DOI: https://doi.org/10.3904/kjim.2023.123                 Background/Aims: Abexol is a mixture of primary aliphatic alcohols purified from beeswax (Apis mellifera), that produces anti-inflammatory, antioxidant and gastroprotective effects, as well as it is safe and well tolerated. To investigate and compare the efficacy and safety of Abexol (suspens..

Gastroenterology / Editorial Could histologic healing be a new treatment target in patients with ulcerative colitis? Soyoung Kim, Sang Hyoung Park Korean J Intern Med. 2024;39(1):2-3.   Published online January 1, 2024 DOI: https://doi.org/10.3904/kjim.2023.539              Web of Science 1    Crossref 2