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Infectious diseases
Public interest in the digital transformation accelerated by the COVID-19 pandemic and perception of its future impact
Joo-Young Park, Kangsun Lee, Doo Ryeon Chung
Korean J Intern Med. 2022;37(6):1223-1233. Published online September 26, 2022
Background/Aims: The coronavirus disease 2019 (COVID-19) pandemic has accelerated digital transformation (DT). We investigated the trend of the public interest in technologies regarding the DT and Koreans’ experiences and their perceptions of the future impact of these technologies.
Methods: Using Google Tr..
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Lopinavir-ritonavir versus hydroxychloroquine for viral clearance and clinical improvement in patients with mild to moderate coronavirus disease 2019
Ji-Won Kim, Eun Jin Kim, Hyun Hee Kwon, Chi Young Jung, Kyung Chan Kim, Jung-Yoon Choe, Hyo-Lim Hong
Korean J Intern Med. 2021;36(Suppl 1):S253-S263. Published online June 16, 2020
Background/Aims: The efficacies of lopinavir-ritonavir or hydroxychloroquine remain to be determined in patients with coronavirus disease 2019 (COVID-19). To compare the virological and clinical responses to lopinavir-ritonavir and hydroxychloroquine treatment in COVID-19 patients.
Methods: This re..
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Cardiology
Effects of renin-angiotensin system blockers on the risk and outcomes of severe acute respiratory syndrome coronavirus 2 infection in patients with hypertension
Jinwoo Lee, Seong Jin Jo, Youngjin Cho, Ji Hyun Lee, Il-Young Oh, Jin Joo Park, Young-Seok Cho, Dong-Ju Choi
Korean J Intern Med. 2021;36(Suppl 1):S123-S131. Published online February 10, 2021
Background/Aims: There are concerns that the use of renin-angiotensin system (RAS) blockers may increase the risk of being infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or progressing to a severe clinical course after infection. This this study aimed to investigate the i..
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Hemato-oncology
The effect of the response to the coronavirus disease pandemic on treatment outcomes in patients with lymphoma and multiple myeloma
Ka-Won Kang, Byung-Hyun Lee, Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Se Ryeon Lee, Hwa Jung Sung, Chul Won Choi, Yong Park, Byung Soo Kim
Korean J Intern Med. 2021;36(6):1459-1470. Published online October 21, 2021
Background/Aims: Relatively little data are available on how the response to the coronavirus disease 2019 (COVID-19) pandemic has affected treatment outcomes in patients receiving chemotherapy for lymphoma or multiple myeloma. We aimed to determine the effect of COVID-19 countermeasures on treatment..
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How lessons learned from the 2015 Middle East respiratory syndrome outbreak affected the response to coronavirus disease 2019 in the Republic of Korea
Tae Un Yang, Ji Yun Noh, Joon-Young Song, Hee Jin Cheong, Woo Joo Kim
Korean J Intern Med. 2021;36(2):271-285. Published online February 5, 2021
The Republic of Korea (ROK) experienced a public health crisis due to Middle East respiratory syndrome (MERS) in 2015 and is currently going through the coronavirus disease 2019 (COVID-19) pandemic. Lessons learned from the disastrous MERS outbreak were ref lected in the preparedness system, and the..
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Angiotensin-converting enzyme 2 and kidney diseases in the era of coronavirus disease 2019
Sang Heon Suh, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
Korean J Intern Med. 2021;36(2):247-262. Published online October 16, 2020
In the decades since the discovery of angiotensin-converting enzyme 2 (ACE2), its protective role in terms of antagonizing activation of the classical renin-angiotensin system (RAS) axis has been recognized in clinical and experimental studies on kidney and cardiovascular diseases. The effects of AC..
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Rapid Communication
Dynamics of viral load and anti-SARS-CoV-2 antibodies in patients with positive RT-PCR results after recovery from COVID-19
Kyoung-Ho Song, Dong-Min Kim, Hyunju Lee, Sin Young Ham, Sang-Min Oh, Hyeonju Jeong, Jongtak Jung, Chang Kyung Kang, Ji Young Park, Yu Min Kang, Ji-Yeon Kim, Jeong Su Park, Kyoung Un Park, Eu Suk Kim, Hong Bin Kim
Korean J Intern Med. 2021;36(1):11-14. Published online November 25, 2020
Recently, the number of patients with coronavirus disease 2019 (COVID-19) who have tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), via the reverse transcription polymerase chain reaction (RT-PCR) test, after recovery has increased; this has caused a dilemma regardin..
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Recommendations for the management of patients with systemic rheumatic diseases during the coronavirus disease pandemic
Mi Ryoung Seo, Ji-Won Kim, Eun-Jung Park, Seung Min Jung, Yoon-Kyoung Sung, Hyungjin Kim, Gunwoo Kim, Hyun-Sook Kim, Myeung-Su Lee, Jisoo Lee, Ji An Hur, Bum Sik Chin, Joong Sik Eom, Han Joo Baek; The Korean College of Rheumatology working group
Korean J Intern Med. 2020;35(6):1317-1332. Published online September 15, 2020
Patients with systemic rheumatic diseases (SRD) are vulnerable for coronavirus disease (COVID-19). The Korean College of Rheumatology recognized the urgent need to develop recommendations for rheumatologists and other physicians to manage patients with SRD during the COVID-19 pandemic. The working g..
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The proposed algorithm for emergency endoscopy during the coronavirus disease 2019 outbreak
Sung Bum Kim, Kook Hyun Kim
Korean J Intern Med. 2020;35(5):1027-1030. Published online July 16, 2020
Following the coronavirus disease 2019 outbreak in China, more than 10,765 patients tested positive for severe acute respiratory syndrome coronavirus 2 from February 18, 2020 to April 30, 2020 in South Korea. Performing emergency endoscopy is extremely challenging from the clinicians’ viewpoint du..
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Rapid Communication
Persistent severe acute respiratory syndrome coronavirus 2 detection after resolution of coronavirus disease 2019-associated symptoms/signs
Se Yoon Park, Soon Gyu Yun, Jeong Won Shin, Bo Young Lee, Hyo-Ju Son, Seungjae Lee, Eunjung Lee, Tae Hyong Kim
Korean J Intern Med. 2020;35(4):793-796. Published online June 19, 2020
There are limited data on the duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory specimens after resolution of coronavirus disease 2019 (COVID-19)-associated symptoms/signs. We determined duration of SARS-CoV-2 virus shedding in symptomatic patients after rem..
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Four cases of coronavirus disease 2019 in the early stage of pandemic of South Korea: a single public hospital experience
Mi Young Ahn, Dong Hyun Oh, Suhyun Kim, Jae-Phil Choi, Ji Hyeon Lee, Young Kyung Lee, Ki Ho Hong
Korean J Intern Med. 2020;35(4):788-792. Published online July 1, 2020
In view of this pandemic, as of February 2020, South Korea has the second highest number of confirmed cases in the world. Herein, we report four confirmed coronavirus disease 2019 (COVID-19) cases in the early stage of the pandemic in South Korea and describe the identification, diagnosis, clinical ..
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Original Article
In vitro activity of lopinavir/ritonavir and hydroxychloroquine against severe acute respiratory syndrome coronavirus 2 at concentrations achievable by usual doses
Chang Kyung Kang, Moon-Woo Seong, Su-Jin Choi, Taek Soo Kim, Pyoeng Gyun Choe, Sang Hoon Song, Nam-Joong Kim, Wan Beom Park, Myoung-don Oh
Korean J Intern Med. 2020;35(4):782-787. Published online May 29, 2020
Background/Aims: As the coronavirus disease-2019 global pandemic progresses, screening of antiviral agents effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is urgently needed. In addition, considering the viral load kinetics of SARS-CoV-2, which peaks early in the illne..
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Lung ultrasound for early diagnosis and severity assessment of pneumonia in patients with coronavirus disease 2019
[corrected-article]
Young-Jae Cho, Kyoung-Ho Song, Yunghee Lee, Joo Heung Yoon, Ji Young Park, Jongtak Jung, Sung Yoon Lim, Hyunju Lee, Ho Il Yoon, Kyoung Un Park, Hong Bin Kim, Eu Suk Kim
Korean J Intern Med. 2020;35(4):771-781. Published online July 1, 2020
Background/Aims: Current evidence supports lung ultrasound as a point-ofcare alternative diagnostic tool for various respiratory diseases. We sought to determine the utility of lung ultrasound for early detection of pneumonia and for assessment of respiratory failure among patients with coronavirus ..
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Selecting coronavirus disease 2019 patients with negligible risk of progression: early experience from non-hospital isolation facility in Korea
Pyoeng Gyun Choe, Eun Kyo Kang, Sun Young Lee, Boram Oh, Dahae Im, Hyo Yeon Lee, Hyemin Jung, Chang Kyung Kang, Min Sun Kim, Wan Beom Park, Eun Hwa Choi, BeLong Cho, Myoung-don Oh, Nam Joong Kim
Korean J Intern Med. 2020;35(4):765-770. Published online May 29, 2020
Background/Aims: As the novel coronavirus (coronavirus disease 2019 [COVID-19]) outbreak progresses rapidly, staying home is recommended for suspected patients; however, the safety of this recommendation is uncertain. In Korea, non-hospital facilities called “living and treatment centers (LTCs)” ..
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A cluster of tertiary transmissions of 2019 novel coronavirus (SARS-CoV-2) in the community from infectors with common cold symptoms
Nam Joong Kim, Pyoeng Gyun Choe, Sang-Joon Park, Jaegyun Lim, Wang Jun Lee, Chang Kyung Kang, Wan Beom Park, Moon-Woo Seong, Myoung-don Oh
Korean J Intern Med. 2020;35(4):758-764. Published online June 11, 2020
Background/Aims: As the global impact of the novel coronavirus disease 2019 (COVID-19) has been severe, many countries have intensified containment activities to eliminate virus transmission, through early detection and isolation strategies. To establish a proper quarantine strategy, it is essential..
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Review
Current laboratory diagnosis of coronavirus disease 2019
Jihyang Lim, Jehoon Lee
Korean J Intern Med. 2020;35(4):741-748. Published online July 1, 2020
Coronavirus disease 2019 (COVID-19) emerged in December 2019 in Wuhan, China; it has since caused a pandemic, with more than 10,000 confirmed cases (> 800,000 tests) in Korea as of May 2020. Real-time reverse transcription polymerase chain reaction (RT-PCR) is currently the most commonly used method..
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Infectious diseases
Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea
Myoung-don Oh, Wan Beom Park, Sang-Won Park, Pyoeng Gyun Choe, Ji Hwan Bang, Kyoung-Ho Song, Eu Suk Kim, Hong Bin Kim, Nam Joong Kim
Korean J Intern Med. 2018;33(2):233-246. Published online February 27, 2018
Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS case..
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Impact of the coronavirus disease 2019 pandemic on the incidence of other infectious diseases in the hematology hospital in Korea
Seohee Oh, Yu-Sun Sung, Mihee Jang, Yong-Jin Kim, Hyun-Wook Park, Dukhee Nho, Dong-Gun Lee, Hyeon Woo Yim, Sung-Yeon Cho
Received November 19, 2023 Accepted February 5, 2024 Published online April 23, 2024
Background/Aims: Since the coronavirus disease 2019 (COVID-19) outbreak, hospitals have implemented infection control measures to minimize the spread of the virus within facilities. This study aimed to investigate the impact of COVID-19 on the incidence of healthcare-associated infections (HCAIs) an..
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