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Pulmonology
Effect of corticosteroid therapy in the early phase of acute respiratory distress syndrome: a propensity-matched cohort study
Moon Seong Baek, Yunkyoung Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2021;36(1):145-153. Published online March 5, 2020
Background/Aims: It is unclear whether corticosteroid use in patients with acute respiratory distress syndrome (ARDS) improves survival. This study aimed to investigate whether the administration of corticosteroids to patients in the early phase of moderate to severe ARDS is associated with improved..
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Hemato-oncology
Derivation and validation of modified early warning score plus SpO2/FiO2 score for predicting acute deterioration of patients with hematological malignancies
Ju-Ry Lee, Youn-Kyoung Jung, Hwa Jung Kim, Younsuck Koh, Chae-Man Lim, Sang-Bum Hong, Jin Won Huh
Korean J Intern Med. 2020;35(6):1477-1488. Published online March 3, 2020
Background/Aims: Scoring systems play an important role in predicting intensive care unit (ICU) admission or estimating the risk of death in critically ill patients with hematological malignancies. We evaluated the modified early warning score (MEWS) for predicting ICU admissions and in-hospital mor..
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Gastroenterology
The quick sepsis-related organ failure score has limited value for predicting adverse outcomes in sepsis patients with liver cirrhosis
Jeongsuk Son, Sunhui Choi, Jin Won Huh, Chae-Man Lim, Younsuck Koh, Kang Mo Kim, Ju Hyun Shim, Young-Suk Lim, Sang-Bum Hong
Korean J Intern Med. 2020;35(4):861-872. Published online October 28, 2019
Background/Aims: The quick Sepsis-related Organ Failure Assessment (qSOFA) is a newly developed risk stratification tool, which has been presented along with a new sepsis definition, to classify infected patients outside of the intensive care unit (ICU). We evaluated the clinical usefulness of qSOFA..
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Effect of vitamin D deficiency in Korean patients with acute respiratory distress syndrome
Sojung Park, Min Gee Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2019;34(3):685-685. Published online April 30, 2019
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Pulmonology
Effect of vitamin D deficiency in Korean patients with acute respiratory distress syndrome
[corrected-article]
Sojung Park, Min Gi Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2018;33(6):1129-1136. Published online June 20, 2018
Background/Aims: Vitamin D modulates innate and adaptive immune responses, and vitamin D deficiency is associated with increased mortality in hospitalized patients with pneumonia. We evaluated the prevalence of vitamin D deficiency in Korean patients with acute respiratory distress syndrome (ARDS) a..
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The effect of an improvement of experience and training in extracorporeal membrane oxygenation management on clinical outcomes
Go-Woon Kim, Younsuck Koh, Chae-Man Lim, Jin Won Huh, Sung Ho Jung, Joon Bum Kim, Sang-Bum Hong
Korean J Intern Med. 2018;33(1):121-129. Published online March 25, 2016
Background/Aims: The use of extracorporeal membrane oxygenation (ECMO) is spreading rapidly, with successful procedures reported in the ECMO for Severe Adult Respiratory failure (CESAR) trial and treatment of the H1N1 pandemic. However, ECMO is associated with a high mortality rate. This study aimed..
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Clinical efficacy of high-flow nasal cannula compared to noninvasive ventilation in patients with post-extubation respiratory failure
Jung-Wan Yoo, Ara Synn, Jin Won Huh, Sang-Bum Hong, Younsuck Koh, Chae-Man Lim
Korean J Intern Med. 2016;31(1):82-88. Published online December 28, 2015
Background/Aims: Post-extubation respiratory failure (PERF) is associated with poor clinica l outcomes. High-f low nasa l cannula (HF NC) ox ygen therapy has been used in patients with respiratory failure, but the clinical benefit in patients with PERF remains unclear. The aim of this study was to e..
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A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock
Jung-Wan Yoo, Ju Ry Lee, Youn Kyung Jung, Sun Hui Choi, Jeong Suk Son, Byung Ju Kang, Tai Sun Park, Jin-Won Huh, Chae-Man Lim, Younsuck Koh, Sang Bum Hong
Korean J Intern Med. 2015;30(4):471-477. Published online June 29, 2015
Background/Aims: The modified early warning score (MEWS) is used to predict patient intensive care unit (ICU) admission and mortality. Lactate (LA) in the blood lactate (BLA) is measured to evaluate disease severity and treatment efficacy in patients with severe sepsis/septic shock. The usefulness o..
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Clinical Meaning of Early Oxygenation Improvement in Severe Acute Respiratory Distress Syndrome under Prolonged Prone Positioning
Kwangha Lee, Mi-Young Kim, Jung-Wan Yoo, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh
Korean J Intern Med. 2010;25(1):58-65. Published online February 26, 2010
Background/AimsVentilating patients with acute respiratory distress syndrome (ARDS) in the prone position has been shown to improve arterial oxygenation, but prolonged prone positioning frequently requires continuous deep sedation, which may be harmful to patients. We evaluated..
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Is Hypercapnea a Predictor of Better Survival in the Patients who Underwent Mechanical Ventilation for Chronic Obstructive Pulmonary Disease (COPD)?
Joo Hun Park, Younsuck Koh, Chae-Man Lim, Sang-Bum Hong, Yeon Mok Oh, Tae Sun Shim, Sang Do Lee, Woo Sung Kim, Dong Soon Kim, Won Dong Kim
Korean J Intern Med. 2006;21(1):1-9. Published online March 30, 2006
BackgroundThere are contradictory reports concerning hypercapnia as a predictor of a better outcome in COPD. This study examined the clinical implications of hypercapnea in COPD patients (M:F = 59:19) who required mechanical ventilation. Methods..
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The Effects of Methylene Blue on Hemodynamic Parameters and Cytokine Levels in Refractory Septic Shock
Byung-Kyu Park, Tae-Sun Shim, Chae-Man Lim, Sang-Do Lee, Woo-Sung Kim, Dong-Soon Kim, Won-Dong Kim, Younsuck Koh
Korean J Intern Med. 2005;20(2):123-128. Published online June 30, 2005
Background/AimsEndogenous nitric oxide (NO) induces the peripheral vasodilation via the activation of guanylate cyclase in patients with septic shock. The purpose of this study was to assess the acute effects of methylene blue (MB), which is an inhibitor of guanylate cyclase, ..
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