Obesity-related heart failure with preserved ejection fraction: diagnostic and therapeutic challenges
Mi-Hyang Jung, Mi-Seung Shin
Korean J Intern Med. 2023;38(2):157-166. Published online February 6, 2023
The prevalence of heart failure with preserved ejection fraction (HFpEF) has increased in recent decades. In particular, obesity-related HFpEF is a distinct and frequently encountered phenotype; however, its diagnosis is complex. Furthermore, the management of obesity-related HFpEF has not been esta..
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Endocrinology-metabolism
Comorbidities associated with high-risk obstructive sleep apnea based on the STOP-BANG questionnaire: a nationwide population-based study
Gene Huh, Kyoung do Han, Yong-Moon Park, Chan-Soon Park, Kyu-na Lee, Eun Young Lee, Jung-Hae Cho
Korean J Intern Med. 2023;38(1):80-92. Published online November 10, 2022
Background/Aims: We investigated the prevalence, associated factors, and comorbidities of high-risk obstructive sleep apnea (OSA) as determined by the STOP-BANG questionnaire in a Korean adult population.
Methods: Data were obtained from 7,650 adults (aged ≥ 40 years) who participated in the Korea ..
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Geriatrics
Four-year changes in central fatness, risk of diabetes, and metabolic control in older adults: a cohort study with mediation analysis
Xue Cai, Dan Luo, Shuling Liu, Ruxue Li, Yanhui Lu, Mingzi Li, Shanhu Qiu
Korean J Intern Med. 2022;37(1):230-240. Published online December 16, 2021
Background/Aims: Older adults are vulnerable to central obesity, while the association of changes in central fatness with risk of diabetes and metabolic control has not been investigated among this particular population. This study was aimed to address these issues.
Methods: A total of 1,815 adults..
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Cardiology
Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
Woo-Hyuk Song, Eun Hui Bae, Jeong Cheon Ahn, Tae Ryom Oh, Yong-Hyun Kim, Jin Seok Kim, Sun-Won Kim, Soo Wan Kim, Kyung-Do Han, Sang-Yup Lim
Korean J Intern Med. 2021;36(Suppl 1):S90-S98. Published online February 25, 2021
Background/Aims: We investigated the impact of obesity on the clinical outcomes following percutaneous coronary intervention (PCI).
Methods: We included South Koreans aged > 20 years who underwent the Korean National Health Screening assessment between 2009 and 2012. Obesity was defined using the b..
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Rheumatology
Pilot study: asymptomatic hyperuricemia patients with obesity and nonalcoholic fatty liver disease have increased risk of double contour sign
Hong Ki Min, Hyonjoung Cho, Sung-Hwan Park
Korean J Intern Med. 2020;35(6):1517-1523. Published online June 13, 2019
Background/Aims: Double contour sign (DCS) is a representative ultrasonographic finding in gout. DCS is evidence of monosodium urate deposit in gouty arthritis and has been identified in some patients with asymptomatic hyperuricemia. However, the specific characteristics of asymptomatic hyperuricemi..
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Endocrinology-metabolism
Optimal body mass index for minimizing the risk for osteoporosis and type 2 diabetes
Ji Hyun Lee, Jung Hee Kim, A Ram Hong, Sang Wan Kim, Chan Soo Shin
Korean J Intern Med. 2020;35(6):1432-1442. Published online October 30, 2019
Background/Aims: Body mass index (BMI) is positively associated with bone mineral density and type 2 diabetes. We investigated an optimal BMI range for osteoporosis and type 2 diabetes.
Methods: This cross-sectional study used data from the Korea National Health and Nutrition Examination Survey (KN..
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Allergy
Effect of the anti-IL-17 antibody on allergic inflammation in an obesity-related asthma model
Lin Liang, Jung Hur, Ji Young Kang, Chin Kook Rhee, Young Kyoon Kim, Sook Young Lee
Korean J Intern Med. 2018;33(6):1210-1223. Published online April 19, 2018
Background/Aims: The co-occurrence of obesity aggravates asthma symptoms. Diet-induced obesity increases helper T cell (TH) 17 cell differentiation in adipose tissue and the spleen. The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pravastatin can potentially be used to treat asthma in o..
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Rheumatology
Metabolic syndrome: prevalence and risk factors in Korean gout patients
Jae Hyun Jung, Gwan Gyu Song, Jong Dae Ji, Young Ho Lee, Jae-Hoon Kim, Young Ho Seo, Sung Jae Choi
Korean J Intern Med. 2018;33(4):815-822. Published online October 12, 2016
Background/Aims: We performed this study to investigate associations between metabolic syndrome, chronic kidney disease (CKD), and gout.
Methods: We reviewed the medical records of 151 patients with gout at the Department of Rheumatology in Korea University Ansan Hospital. The following measures we..
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Endocrinology-metabolism
Metabolically healthy obesity: a friend or foe?
Chang Hee Jung, Woo Je Lee, Kee-Ho Song
Korean J Intern Med. 2017;32(4):611-621. Published online June 5, 2017
Obesity is associated with a reduced life expectancy, largely because obese individuals are at an increased risk of type 2 diabetes, cardiovascular disease, and several types of cancer. Much interest has recently focused on the concept of “all obesity is not created equally.” Obese individuals wi..
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Linking resistin, inflammation, and cardiometabolic diseases
Hyeong Kyu Park, Mi Kyung Kwak, Hye Jeong Kim, Rexford S. Ahima
Korean J Intern Med. 2017;32(2):239-247. Published online February 16, 2017
Adipose tissue secretes a variety of bioactive substances that are associated with chronic inflammation, insulin resistance, and an increased risk of type 2 diabetes mellitus. While resistin was first known as an adipocyte-secreted hormone (adipokine) linked to obesity and insulin resistance in rode..
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Sarcopenia and sarcopenic obesity
Kyung Mook Choi
Korean J Intern Med. 2016;31(6):1054-1060. Published online November 1, 2016
Sarcopenia is an age-associated loss of muscle mass and decline in muscle strength; it is common in older adults and is associated with significant morbidity and mortality. Despite its prevalence, there is currently no universally adopted definition of sarcopenia. In addition to low muscle mass meas..
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Relationship between metabolic syndrome and thyroid nodules in healthy Koreans
Juyoung Shin, Min-Hee Kim, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Dong-Jun Lim
Korean J Intern Med. 2016;31(1):98-105. Published online December 28, 2015
Background/Aims: This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans.
Methods: We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine c..
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Gastroenterology
Neck circumference correlates with tumor size and lateral lymph node metastasis in men with small papillary thyroid carcinoma
Mi Ra Kim, Sang Soo Kim, Jung Eun Huh, Byung Joo Lee, Jin Choon Lee, Yun Kyung Jeon, Bo Hyun Kim, Seong Jang Kim, Soo Geun Wang, Yong Ki Kim, In Joo Kim
Korean J Intern Med. 2013;28(1):62-71. Published online December 28, 2012
Background/AimsObesity is correlated with numerous diseases, including thyroid cancer, but the clinical significance of obesity with regard to the clinical characteristics of thyroid cancer remains unclear. Neck circumference is an index of upper-body adipose tissue distributi..
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Endocrinology-metabolism
Gender disparity in the secular trends for obesity prevalence in Korea: analyses based on the KNHANES 1998-2009
Sang Youl Rhee, Seok Won Park, Dae Jung Kim, Jeongtaek Woo
Korean J Intern Med. 2013;28(1):29-34. Published online December 28, 2012
Background/AimsA similar gender-associated trend in obesity is observed worldwide. Nevertheless, systematic analyses of gender-specific characteristics in the general Korean population are rare. MethodsWe analyzed the prevalence of obesity in Ko..
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The Contribution of Abdominal Obesity and Dyslipidemia to Metabolic Syndrome in Psychiatric Patients
Sung-Hwan Kim, Kiwon Kim, Mi Hyang Kwak, Hak Jin Kim, Hong-Sup Kim, Ki Hoon Han
Korean J Intern Med. 2010;25(2):168-173. Published online June 1, 2010
Background/AimsMetabolic syndrome is an emerging risk factor for cardiovascular disease. This study investigated the prevalence of metabolic syndrome among psychiatric patients in order to identify the dominant factors of metabolic syndrome. Methods
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The Body Mass Index as a Prognostic Factor of Critical Care
So Yeon Lim, So I Kim, Yon Ju Ryu, Jin Hwa Lee, Eun Mi Chun, Jung Hyun Chang
Korean J Intern Med. 2010;25(2):162-167. Published online June 1, 2010
Background/AimsObesity is a worldwide concern, but its influence on critical care outcomes is not well understood. We tested the hypothesis that abnormal body mass index (BMI) would be an independent predictor of higher mortality rates in intensive care unit (ICU).
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