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Gastroenterology / Review
Artificial intelligence in colonoscopy: from detection to diagnosis
Eun Sun Kim, Kwang-Sig Lee
Korean J Intern Med. 2024;39(4):555-562. Published online May 2, 2024
This study reviews the recent progress of artificial intelligence for colonoscopy from detection to diagnosis. The source of data was 27 original studies in PubMed. The search terms were “colonoscopy” (title) and “deep learning” (abstract). The eligibility criteria were: (1) the dependent varia..
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Gastroenterology / Review
Strategies to improve screening colonoscopy quality for the prevention of colorectal cancer
Joo Hye Song, Eun Ran Kim
Korean J Intern Med. 2024;39(4):547-554. Published online January 22, 2024
The incidence and mortality of colorectal cancer (CRC) have decreased through regular screening colonoscopy, surveillance, and endoscopic treatment. However, CRC can still be diagnosed after negative colonoscopy. Such CRC is called interval CRC and accounts for 1.8–9.0% of all CRC cases. Most case..
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Infectious diseases / Original Article
Impact of the coronavirus disease 2019 pandemic on the incidence of other infectious diseases in the hematology hospital in Korea
Seohee Oh, Yu-Sun Sung, Mihee Jang, Yong-Jin Kim, Hyun-Wook Park, Dukhee Nho, Dong-Gun Lee, Hyeon Woo Yim, Sung-Yeon Cho
Korean J Intern Med. 2024;39(3):513-523. Published online April 23, 2024
Background/Aims: Since the coronavirus disease 2019 (COVID-19) outbreak, hospitals have implemented infection control measures to minimize the spread of the virus within facilities. This study aimed to investigate the impact of COVID-19 on the incidence of healthcare-associated infections (HCAIs) an..
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Pulmonology / Original Article
Risk factors for progressing to critical illness in patients with hospital-acquired COVID-19
Kyung-Eui Lee, Jinwoo Lee, Sang-Min Lee, Hong Yeul Lee
Korean J Intern Med. 2024;39(3):477-487. Published online April 18, 2024
Background/Aims: Risk factors for progression to critical illness in hospital-acquired coronavirus disease 2019 (COVID-19) remain unknown. Here, we assessed the incidence and risk factors for progression to critical illness and determined their effects on clinical outcomes in patients with hospital-..
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Gastroenterology / Original Article
Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis
Aryoung Kim, Byeong Geun Song, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Myung Ji Goh
Korean J Intern Med. 2024;39(3):448-457. Published online April 30, 2024
Background/Aims: Improved knowledge of local epidemiology and predicting risk factors of multidrug-resistant (MDR) bacteria are required to optimize the management of infections. This study examined local epidemiology and antibiotic resistance patterns of liver cirrhosis (LC) patients and evaluated ..
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Gastroenterology / Original Article
Predicting Helicobacter pylori infection from endoscopic features
Jun-young Seo, Ji Yong Ahn, Seonok Kim, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
Korean J Intern Med. 2024;39(3):439-447. Published online April 30, 2024
Background: Helicobacter pylori infection, prevalent in more than half of the global population, is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. The effectiveness of early diagnosis and treatment in preventing gastric cancer highlights the nee..
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Infectious diseases / Review
Role of biomarkers in antimicrobial stewardship: physicians’ perspectives
Hyeri Seok, Dae Won Park
Korean J Intern Med. 2024;39(3):413-429. Published online April 30, 2024
Biomarkers are playing an increasingly important role in antimicrobial stewardship. Their applications have included use in algorithms that evaluate suspected bacterial infections or provide guidance on when to start or stop antibiotic therapy, or when therapy should be repeated over a short period ..
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Infectious diseases / Review
Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea
Soo Jin Lee, Raeseok Lee, Sung-Yeon Cho, Dukhee Nho, Hye Lim Ahn, Dong-Gun Lee
Korean J Intern Med. 2024;39(3):399-412. Published online April 30, 2024
Antimicrobial stewardship programs (ASPs) can lower antibiotic use, decrease medical expenses, prevent the emergence of resistant bacteria, and enhance treatment for infectious diseases. This study summarizes the stepwise implementation and effects of ASPs in a single university-affiliated tertiary ..
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Infectious diseases / Review
Quantitative and qualitative evaluation of antimicrobial usage: the first step for antimicrobial stewardship
Song Mi Moon, Bongyoung Kim, Hong Bin Kim
Korean J Intern Med. 2024;39(3):383-398. Published online April 30, 2024
The identification of antimicrobial use patterns is essential for determining key targets for antimicrobial stewardship interventions and evaluating the effectiveness thereof. Accurately identifying antimicrobial use patterns requires quantitative evaluation, which focuses on measuring the quantity ..
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Hemato-oncology / Original Article
Prognostic Significance Of Sequential 18f-fdg Pet/Ct During Frontline Treatment Of Peripheral T Cell Lymphomas
Ga-Young Song, Sung-Hoon Jung, Seo-Yeon Ahn, Mihee Kim, Jae-Sook Ahn, Je-Jung Lee, Hyeoung-Joon Kim, Jang Bae Moon, Su Woong Yoo, Seong Young Kwon, Jung-Joon Min, Hee-Seung Bom, Sae-Ryung Kang, Deok-Hwan Yang
Korean J Intern Med. 2024;39(2):327-337. Published online January 25, 2024
Background/Aims: The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemo..
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Pulmonology / Original Article
Clinical impact of pleural fluid carcinoembryonic antigen on therapeutic strategy and efficacy in lung adenocarcinoma patients with malignant pleural effusion
Jaehee Lee, Deok Heon Lee, Ji Eun Park, Yong Hoon Lee, Sun Ha Choi, Hyewon Seo, Seung Soo Yoo, Shin Yup Lee, Seung-Ick Cha, Jae Yong Park, Chang Ho Kim
Korean J Intern Med. 2024;39(2):318-326. Published online February 14, 2024
Background/Aims: Epidermal growth factor receptor (EGFR) mutation is important in determining the treatment strategy for advanced lung cancer patients with malignant pleural effusion (MPE). Contrary to serum carcinoembryonic antigen (S-CEA) levels, the associations between pleural fluid CEA (PF-CEA)..
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Cardiology / Original Article
Association of epicardial adipose tissue with metabolic risk factors on cardiovascular outcomes: serial coronary computed tomography angiography study
Sungjoon Park, Dong Eun Kim, Su Min Kim, JungMin Choi, Sang Joon Park, Hae-Young Lee, Eun Ju Chun
Korean J Intern Med. 2024;39(2):283-294. Published online February 14, 2024
Background/Aims: Epicardial adipose tissue (EAT) shares pathophysiological properties with other visceral fats and potentially triggers local inflammation. However, the association of EAT with cardiovascular disease (CVD) is still debatable. The study aimed to observe the changes and associations in..
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Gastroenterology / Original Article
Endoscopic mucosal resection using anchored snare Tip-in versus precut technique for small rectal neuroendocrine tumors
Seung Wook Hong, Dong-Hoon Yang, Yoo Jin Lee, Dong Hoon Baek, Jaeyoung Chun, Hyun Gun Kim, Sung Joo Kim, Seung-Mo Hong, Dae-Seong Myung
Korean J Intern Med. 2024;39(2):238-247. Published online December 8, 2023
Background/Aims: Small rectal neuroendocrine tumors (NETs) can be treated with modified endoscopic mucosal resection (EMR). However, an optimal EMR method remains to be established. We aimed to assess the non-inferiority of Tip-in EMR versus precut EMR (EMR-P) for treating rectal NETs.
Methods: Thi..
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Gastroenterology / Original Article
The combined use of anti-peptic agents is associated with an increased risk of osteoporotic fracture: a nationwide case-control study
Dong Jun Oh, Ji Hyung Nam, Hyun Seok Lee, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):228-237. Published online February 7, 2024
Background/Aims: Long-term use of acid suppressants such as proton pump inhibitors (PPIs) and histamine 2 receptor antagonist (H2RA) has been associated with the risk of osteoporotic fracture. Acid suppressants and muco-protective agents (MPAs) are often used together as anti-ulcer agents. We evalua..
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Rheumatology / Original Article
Clinical characteristics and prognostic factors of non-tuberculous mycobacterial disease in patients with rheumatoid arthritis
Hyemin Kim, Soyoung Lee, Ji-Won Kim, Ju-Yang Jung, Chang-Hee Suh, Hyoun-Ah Kim
Korean J Intern Med. 2024;39(1):172-183. Published online November 30, 2023
Background/Aims: This study aimed to identify the clinical characteristics of patients with concurrent rheumatoid arthritis (RA) and suspected non-tuberculous mycobacterial (NTM) infections as well as determine their prognostic factors.
Methods: We retrospectively reviewed the medical records of 91..
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Pulmonology / Original Article
Sex differences in chronic obstructive pulmonary disease characteristics: the Korea National Health and Nutrition Examination Survey 2007–2018
Moon Seong Baek, Haegwang Shin, Kang-Mo Gu, Hae In Jung, Won Young Kim, Jae-Woo Jung, Jong-Wook Shin, Sun-Young Jung, Jae-Yeol Kim
Korean J Intern Med. 2024;39(1):137-147. Published online December 14, 2023
Background/Aims: Chronic obstructive pulmonary disease (COPD) is less prevalent in females than males, but it affects mortality in females. There may be sex differences in the clinical characteristics of COPD.
Methods: We analyzed the Korea National Health and Nutrition Examination Survey dataset f..
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Cardiology / Original Article
Time to presentation and mortality outcomes among patients with diabetes and acute myocardial infarction
Min-A Shin, Seok Oh, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong
Korean J Intern Med. 2024;39(1):110-122. Published online December 11, 2023
Background/Aims: Due to limited real-world evidence on the association between time to presentation (T2P) and outcomes following acute myocardial infarction and diabetes (AMI-DM), we investigated the characteristics of patients with AMI-DM and their outcomes based on their T2P.
Methods: 4,455 patie..
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Gastroenterology / Original Article
Usefulness of nasal cavity evaluation before high-resolution esophageal manometry in high-risk patients
Hyun Jin Min, Jae Yong Park
Korean J Intern Med. 2024;39(1):86-94. Published online November 30, 2023
Background/Aims: A catheter is inserted through the nasal cavity during high-resolution esophageal manometry (HRM), which may cause adverse events such as pain or epistaxis. Despite these possible safety considerations, studies on this subject are very limited. We aimed to investigate the usefulness..
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Gastroenterology / Original Article
Risk factors for anticoagulant-associated gastrointestinal hemorrhage: a systematic review and meta-analysis
Fuxin Ma, Shuyi Wu, Shiqi Li, Zhiwei Zeng, Jinhua Zhang
Korean J Intern Med. 2024;39(1):77-85. Published online December 8, 2023
Background/Aims: There may be many predictors of anticoagulation-related gastrointestinal bleeding (GIB), but until now, systematic reviews and assessments of the certainty of the evidence have not been published. We conducted a systematic review to identify all risk factors for anticoagulant-associ..
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Gastroenterology / Original Article
Comparative study of the efficacy and safety of Abexol (suspension versus tablets) in patients with gastrointestinal symptoms
Alfredo Hierro González, Julio César Fernández Travieso, Yoandy Hernández Casas, Susana Borges González, María de los Angeles Camacho Morales, Elena Ferrer Batallie, Anaisa Roja Carralera, Yenney Reyes Nuñez, Sarahi Mendoza Castaño, Maytee Robaina García, Diana Margarita Rey Kaba
Korean J Intern Med. 2024;39(1):57-67. Published online November 30, 2023
Background/Aims: Abexol is a mixture of primary aliphatic alcohols purified from beeswax (Apis mellifera), that produces anti-inflammatory, antioxidant and gastroprotective effects, as well as it is safe and well tolerated. To investigate and compare the efficacy and safety of Abexol (suspens..
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