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Rheumatology
Overlap syndrome of systemic sclerosis with antineutrophil cytoplasmic antibody-associated vasculitis according to 2022 ACR/EULAR criteria
Jang Woo Ha, Jung Yoon Pyo, Sung Soo Ahn, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
Korean J Intern Med. 2024;39(3):524-536. Published online January 29, 2024
Background/Aims: This study applied the 2022 American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR) criteria for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) to patients with systemic sclerosis (SSc) and investigated the frequency ..
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Infectious diseases
Clinical significance of antinuclear antibody positivity in patients with severe coronavirus disease 2019
Soo Hyun Park, Jin Woong Suh, Kyung-Sook Yang, Jeong Yeon Kim, Sun Bean Kim, Jang Wook Sohn, Young Kyung Yoon
Korean J Intern Med. 2023;38(3):417-426. Published online April 6, 2023
Background/Aims: This study aimed to investigate the clinical characteristics and outcomes of fluorescent antinuclear antibody (FANA)-positive patients admitted for coronavirus disease 2019 (COVID‐19) and identify FANA as a prognostic factor of mortality.
Methods: This retrospective study was con..
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A study on changes in lung function, neutralizing antibodies, and symptoms of adult patients hospitalized with COVID-19
Moon Seong Baek, Seong-Ho Choi, Won-Young Kim, Min-Chul Kim, Eun-Jeong Joo, Mi Suk Lee, Hyun Ah Kim, Sook In Jung, Yu Shi Nae, Bongyoung Kim, Yaeji Lim, Jin-Won Chung
Korean J Intern Med. 2023;38(1):101-112. Published online October 25, 2022
Background/Aims: To identify changes in symptoms and pulmonary sequelae in patients with coronavirus disease 2019 (COVID-19).
Methods: Patients with COVID-19 hospitalized at seven university hospitals in Korea between February 2020 and February 2021 were enrolled, provided they had ≥ 1 outpatient..
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Proprotein convertase subtilisin/kexin type 9 inhibition in cardiovascular disease: current status and future perspectives
Kyung Hoon Cho, Young Joon Hong
Korean J Intern Med. 2020;35(5):1045-1058. Published online August 28, 2020
Proprotein convertase subtilisin/kexin type 9 (PCSK9) targets the degradation of low-density lipoprotein (LDL) receptors; it has been proved that its inhibition improves cardiovascular outcomes in patients with established atherosclerotic cardiovascular disease (ASCVD). Herein, we review the current..
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Nephrology
Seropositive rate of the anti-hepatitis A immunoglobulin G antibody in maintenance hemodialysis subjects from two hospitals in Korea
Hyunsuk Kim, Jiwon Ryu, Young-Ki Lee, Myung Jin Choi, Ajin Cho, Ja-Ryong Koo, Sae Yun Baik, Eun Hee Lee, Jong-Woo Yoon, Jung-Woo Noh
Korean J Intern Med. 2019;34(6):1297-1303. Published online February 23, 2018
Background/Aims: Hepatitis A virus (HAV) is a self-limiting infectious disease, but 1% of subjects develop fulminant hepatitis. The prevalence of the anti-HAV immunoglobulin G (IgG) antibody in hemodialysis subjects in Korea remains unknown. The purpose of this study was to describe and compare the ..
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Rheumatology
The evaluation of cellular immune function in elderly patients with systemic lupus erythematosus
Kun Men, Yu Chen, Jingwei Zhang, Dianjun Wei
Korean J Intern Med. 2019;34(4):932-937. Published online November 29, 2017
Background/Aims: To evaluate cellular immune function in systemic lupus erythematosus (SLE) patients over 60 years old, the association between antinuclear antibody (ANA) titers and the ratio of CD4+ /CD8+ was analyzed in this study. The distribution of ANAs and extractable nu..
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Microscopic polyangiitis with crescentic glomerulonephritis initially presenting as acute pancreatitis
A Young Cho, Byeong Gwan Kim, Sang Sun Kim, Seong Hee Lee, Hong Shik Shin, Yeong Jin Choi, In O Sun
Korean J Intern Med. 2016;31(2):403-405. Published online February 11, 2016
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Co-existing proteinase 3-antineutrophil cytoplasmic antibody-associated vasculitis with immunoglobulin A nephropathy
Adem Kucuk, Yalcin Solak, Abduzhappar Gaipov, Sinan Bagcaci, Hasan Esen, Suleyman Turk, Recep Tunc
Korean J Intern Med. 2016;31(1):194-196. Published online December 28, 2015
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Endocrinology-metabolism
Reference interval for thyrotropin in a ultrasonography screened Korean population
Mijin Kim, Tae Yong Kim, Soo Han Kim, Yunkyoung Lee, Su-yeon Park, Hyung-Don Kim, Hyemi Kwon, Yun Mi Choi, Eun Kyung Jang, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
Korean J Intern Med. 2015;30(3):335-344. Published online April 29, 2015
Background/Aims: The diagnostic accuracy of thyroid dysfunctions is primarily affected by the validity of the reference interval for serum thyroid-stimulating hormone (TSH). Thus, the present study aimed to establish a reference interval for TSH using a normal Korean population.
Methods: This study..
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Allergy
Clinical features and prognostic factors of Churg-Strauss syndrome
Mi-Yeong Kim, Kyoung-Hee Sohn, Woo-Jung Song, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Hye-Ryun Kang
Korean J Intern Med. 2014;29(1):85-95. Published online January 2, 2014
Background/Aims: Churg-Strauss syndrome (CSS) is a rare systemic necrotizing
small-vessel vasculitis, with accompanying bronchial asthma, eosinophilia, and
eosinophilic infiltration of various tissues. The purposes of our study were to
characterize the clinical features of CSS and to identify fac..
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Cardiology
Antiangiogenesis therapy: an update after the first
decade
Sandro De Falco
Korean J Intern Med. 2014;29(1):1-11. Published online January 2, 2014
Angiogenesis is a complex biological phenomenon that forms new blood vessels
from the pre-existing vasculature. Aberrant angiogenesis has been implicated in
a variety of diseases such as cancer, atherosclerosis, arthritis, obesity, pulmonary
hypertension, diabetic retinopathy, and age-related mac..
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Risk Factors of Cryptogenic Hepatocellular Carcinoma in Patients with Low Body Mass Index or without Metabolic Syndrome
Hwa Young Song, Hyo Keun Lee, June Sung Lee, Jong Yeon Kim, Yun Hyuk Yim, Tae Jun Song, Won Ki Bae, Nam-Hoon Kim, Kyung-Ah Kim
Korean J Intern Med. 2012;27(1):47-52. Published online February 28, 2012
Background/AimsMany patients are diagnosed with cryptogenic hepatocellular carcinoma (HCC) without metabolic syndrome (MS). We investigated the risk factors for cryptogenic HCC in patients with a low body mass index (BMI) or without MS. MethodsT..
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Clinical Implications of Elevated Antiphospholipid Antibodies in Adult Patients with Primary Immune Thrombocytopenia
Young-Joon Yang, Gak-Won Yun, Ik-Chan Song, Seung-Woo Baek, Kyu-Seop Lee, Hye Won Ryu, Myung-Won Lee, Hyo-Jin Lee, Hwan-Jung Yun, Samyong Kim, Deog-Yeon Jo
Korean J Intern Med. 2011;26(4):449-454. Published online November 28, 2011
Background/AimsAntiphospholipid antibodies (aPL) have been detected in various proportions of patients with primary immune thrombocytopenia (ITP), but the clinical significance of this is debatable. The present study aimed to determine the frequency and clinical implications o..
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Complete Atrioventricular Block in Adult Sjögren's Syndrome with Anti-Ro Autoantibody
Myung Jun Sung, Sung-Hoon Park, Seong-Kyu Kim, Young-Soo Lee, Chul-Yeon Park, Jung-Yoon Choe
Korean J Intern Med. 2011;26(2):213-215. Published online June 1, 2011
Anti-Ro autoantibody is associated with Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), and neonatal lupus syndrome (i.e., congenital complete heart block in newborns). Generally, the adult atrioventricular (AV) node is believed to be relatively resistant to the scarring effects of..
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