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Original Article

March 25, 2025


Effect of tegoprazan on temporal variability of platelet reactivity in patients treated with clopidogrel after coronary stenting
Oh-Hyun Lee, Ji Woong Roh, Yongcheol Kim, et al.
Korean J Intern Med. 2025;40(5):759-766.

1. We demonstrated that clopidogrel reactivity over time after PCI were similar between the tegoprazan and the PPI groups. 2. The incidence of high on-treatment platelet reactivity over time was also...

Original Article

July 17, 2025


Predicted pro-inflammatory high-sensitivity C-reactive protein score and inflammatory bowel disease: a cross-sectional study
Dong Hyun Kim, Akinkunmi Paul Okekunle, Jioh Kang, et al.
Korean J Intern Med. 2025;40(5):734-746.

1. Higher predicted pro-inflammatory hs-CRP scores were associated with a higher prevalence of IBD, especially UC, but not CD. 2. The predicted pro-inflammatory hs-CRP scores also demonstrated distinct patterns in discriminating...

Original Article

July 25, 2025


Association of kidney function and proteinuria with lower-extremity dysfunction in older Korean adults: a cross-sectional study
Bongjo Kim, Eun-Bin Lim, Young Sang Lyu, et al.
Korean J Intern Med. 2025;40(5):823-834.

1. A U-shaped relationship exists between renal function and lower-extremity dysfunction, with both low and elevated eGFR levels linked to increased impairment risk. 2. Proteinuria is independently associated with a higher...

Original Article

August 26, 2025


Automatic quantitative analysis of atherosclerotic aortic plaques in patients with embolic cerebral infarction using deep learning
Hye Jin Bang, Jae-Hyeong Park, Sun Geu Chae, et al.
Korean J Intern Med. 2025;40(5):767-779.

1. A U-net-based automated segmentation model was used to estimate the aortic plaque area in patients with ESUS. 2. This model may aid in identifying complex aortic plaques with both speed...

Original Article

August 26, 2025


Efficacy and safety of HL-301 compared with erdosteine in acute bronchitis: a randomized, double-blind, non-inferiority trial
Ji-Yong Moon, Joon Young Choi, Youlim Kim, et al.
Korean J Intern Med. 2025;40(5):790-800.

1. HL-301 (300 mg twice daily) demonstrated non-inferiority to erdosteine (300 mg three times daily) in reducing the Bronchitis Severity Score (BSS) in patients with acute bronchitis after seven days...

Original Article

August 26, 2025


The early impact of COVID-19 vaccines on major events in cardiac, pulmonary, and thromboembolic disease: a population-based study
Myeong Geun Choi, Min-Ho Kim, Eun Mi Chun
Korean J Intern Med. 2025;40(5):801-812.

1. This study evaluated the incidence of COVID-19 vaccine-related major events. 2. Vaccination was associated with the development of myocarditis, especially with mRNA vaccines. 3. Vaccination significantly lowered the risk of MI,...

Original Article

August 26, 2025


Association between metabolic dysfunction-associated steatotic liver disease and the risk of thyroid cancer: a nationwide cohort study
Jeongmin Lee, Jeongeun Kwak, Min-Hee Kim, et al.
Korean J Intern Med. 2025;40(5):813-822.

1. This retrospective cohort study investigated the risk of thyroid cancer associated with MASLD using a nationally representative sample of 121,479 adults from the Korean National Health Insurance database. 2. MASLD...

Original Article

August 26, 2025


Comprehensive analysis of patients with rheumatoid arthritis associated interstitial lung disease
Ji-Won Kim, Ju-Yang Jung, Chang-Hee Suh, et al.
Korean J Intern Med. 2025;40(5):845-855.

1. The UIP pattern and ILD duration significantly influence disease progression and mortality in RAILD patients. 2. Methotrexate use did not show a significant impact on the progression or mortality of...

Original Article

August 29, 2025


Live zoster vaccination and hepatobiliary risk reduction: a nationwide South Korean study
Junyeol Kim, Kyeongmin Lee, Jiyeon Oh, et al.
Korean J Intern Med. 2025;40(5):747-758.

1. Live zoster vaccination was associated with a reduced risk of hepatobiliary and pancreatic diseases. 2. The protective effect persisted for up to 8 years, peaking at 1–4 years after vaccination,...

Original Article

August 29, 2025


Impact of guideline-directed medical therapy on the cardiac or non-cardiac death in acute myocardial infarction
Jin-Ho Choi, Dahee Hyun, Seung Ho Hur, et al.
Korean J Intern Med. 2025;40(5):780-789.

1. Propensity score-matched 2,700 matched pairs of AMI patients (mean age 64.9 years) derived from the KAMIR-NIH registry (2011–2015) were evaluated for 3 years. 2. Both cardiac death (5.0% vs. 8.6%;...

Original Article

August 29, 2025


Factors influencing delayed attainment of low disease activity in rheumatoid arthritis patients continuing targeted therapy
Yeo-Jin Song, Soo-Kyung Cho, Se Rim Choi, et al.
Korean J Intern Med. 2025;40(5):835-844.

1. Among 456 patients with RA receiving targeted therapy, 213 (46.7%) continued with their initial treatment regimen despite not achieving LDA by week 24. 2. Among patients who did not achieve...
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    • Current Issue
    Volume 40(5); Sep 2025
    Hidden benefits beyond herpes zoster: a potential preventive strategy against hepatobiliary diseases
    Dong Wook Kim, Tae Jun Song
    Korean J Intern Med. 2025;40(5):691-692.

    Editorial

    August 29, 2025
    Turning evidence into action: the real challenge of guideline-directed medical therapy in acute myocardial infarction
    Jong Shin Woo
    Korean J Intern Med. 2025;40(5):693-695.

    Editorial

    August 29, 2025
    Physical activity for prevention of cardiovascular disease: consensus statement of Korean Society of Cardio-cerebrovascular Disease Prevention
    Ye Seul Yang, Eu Jeong Ku, Seung-Hyun Ko, et al.
    Korean J Intern Med. 2025;40(5):696-709.

    Review

    August 29, 2025
    Diagnostic approach for incidental pulmonary nodules
    SeungYong Park, Seoung Ju Park
    Korean J Intern Med. 2025;40(5):710-724.

    Review

    August 26, 2025
    Appropriate timing of antibiotic initiation in patients with sepsis or septic shock: a systematic review and meta-analysis
    Nam Su Ku, Yongseop Lee, Dae Won Park
    Korean J Intern Med. 2025;40(5):725-733.

    Review

    August 26, 2025
    Predicted pro-inflammatory high-sensitivity C-reactive protein score and inflammatory bowel disease: a cross-sectional study
    Dong Hyun Kim, Akinkunmi Paul Okekunle, Jioh Kang, et al.
    Korean J Intern Med. 2025;40(5):734-746.

    Original Article

    July 17, 2025
    Live zoster vaccination and hepatobiliary risk reduction: a nationwide South Korean study
    Junyeol Kim, Kyeongmin Lee, Jiyeon Oh, et al.
    Korean J Intern Med. 2025;40(5):747-758.

    Original Article

    August 29, 2025
    Effect of tegoprazan on temporal variability of platelet reactivity in patients treated with clopidogrel after coronary stenting
    Oh-Hyun Lee, Ji Woong Roh, Yongcheol Kim, et al.
    Korean J Intern Med. 2025;40(5):759-766.

    Original Article

    March 25, 2025
    Automatic quantitative analysis of atherosclerotic aortic plaques in patients with embolic cerebral infarction using deep learning
    Hye Jin Bang, Jae-Hyeong Park, Sun Geu Chae, et al.
    Korean J Intern Med. 2025;40(5):767-779.

    Original Article

    August 26, 2025
    Impact of guideline-directed medical therapy on the cardiac or non-cardiac death in acute myocardial infarction
    Jin-Ho Choi, Dahee Hyun, Seung Ho Hur, et al.
    Korean J Intern Med. 2025;40(5):780-789.

    Original Article

    August 29, 2025
    Efficacy and safety of HL-301 compared with erdosteine in acute bronchitis: a randomized, double-blind, non-inferiority trial
    Ji-Yong Moon, Joon Young Choi, Youlim Kim, et al.
    Korean J Intern Med. 2025;40(5):790-800.

    Original Article

    August 26, 2025
    The early impact of COVID-19 vaccines on major events in cardiac, pulmonary, and thromboembolic disease: a population-based study
    Myeong Geun Choi, Min-Ho Kim, Eun Mi Chun
    Korean J Intern Med. 2025;40(5):801-812.

    Original Article

    August 26, 2025
    Association between metabolic dysfunction-associated steatotic liver disease and the risk of thyroid cancer: a nationwide cohort study
    Jeongmin Lee, Jeongeun Kwak, Min-Hee Kim, et al.
    Korean J Intern Med. 2025;40(5):813-822.

    Original Article

    August 26, 2025
    Association of kidney function and proteinuria with lower-extremity dysfunction in older Korean adults: a cross-sectional study
    Bongjo Kim, Eun-Bin Lim, Young Sang Lyu, et al.
    Korean J Intern Med. 2025;40(5):823-834.

    Original Article

    July 25, 2025
    Factors influencing delayed attainment of low disease activity in rheumatoid arthritis patients continuing targeted therapy
    Yeo-Jin Song, Soo-Kyung Cho, Se Rim Choi, et al.
    Korean J Intern Med. 2025;40(5):835-844.

    Original Article

    August 29, 2025
    Comprehensive analysis of patients with rheumatoid arthritis associated interstitial lung disease
    Ji-Won Kim, Ju-Yang Jung, Chang-Hee Suh, et al.
    Korean J Intern Med. 2025;40(5):845-855.

    Original Article

    August 26, 2025
    Findings suggestive of Fanconi syndrome and multiple myeloma
    Hwa-Young Lee, Sung Gyul Lim, Han Sang Lee, et al.
    Korean J Intern Med. 2025;40(5):856-857.

    Image of interest

    July 17, 2025
    Leiomyosarcoma at popliteal vein presented as unilateral leg edema in a patient with kidney transplantation
    Sang Heon Song
    Korean J Intern Med. 2025;40(5):858-859.

    Image of interest

    August 26, 2025

    Korean Journal of
    Internal Medicine

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    Online ISSN: 2005-6648

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